Literature summary extracted from

Hicks, K.A.; Hartman, H.L.; Fierke, C.A.
Upstream polybasic region in peptides enhances dual specificity for prenylation by both farnesyltransferase and geranylgeranyltransferase type I (2005), Biochemistry, 44, 15325-15333.

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.5.1.59	Zn2+	catalytic zinc ion coordinates the thiol of the peptide substrate	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.59	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.59	geranylgeranyl diphosphate + dansyl-Thr-Lys-Cys-Val-Ile-Met	-	Escherichia coli	diphosphate + dansyl-Thr-Lys-(S-geranylgeranyl)-Cys-Val-Ile-Met	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.5.1.59	geranylgeranyltransferase type I	-	Escherichia coli
2.5.1.59	GGTaseI	-	Escherichia coli

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Release 2023.1 (January 2023)