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Literature summary extracted from

  • Tarasiuk, J.; Mazerski, J.; Tkaczyk-Gobis, K.; Borowski, E.
    Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies (2005), Eur. J. Med. Chem., 40, 321-328.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
7.1.1.2 0.036
-
 ferricytochrome c in the presence of 0.1 mM daunorubicin Mus musculus
7.1.1.2 0.0571
-
 ferricytochrome c in the presence of 0.1 mM mitoxantrone Mus musculus
7.1.1.2 0.0684
-
 ferricytochrome c in the presence of 0.1 mM ametantrone Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.2 mitochondrion
-
 Mus musculus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 2 ferricytochrome c + NADH
-
 Mus musculus 2 ferrocytochrome c + NAD+ + H+
-
 ?
7.1.1.2 NADH + ferricytochrome c
-
 Mus musculus NAD+ + H+ + ferrocytochrome c
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.2 mitochondrial NADH dehydrogenase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.2 NADH
-
 Mus musculus