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Literature summary extracted from

  • Yan, R.; Wan, L.; Pizzorno, G.; Cao, D.
    Uridine phosphorylase in breast cancer: a new prognostic factor? (2006), Front. Biosci., 11, 2759-2766.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.3 0.02
-
 alpha-D-ribose-1-phosphate cosubstrate: 5-fluorouracil, enzyme from liver Rattus norvegicus
2.4.2.3 0.03
-
 alpha-D-ribose-1-phosphate cosubstrate: uracil, enzyme from liver Rattus norvegicus
2.4.2.3 0.036
-
 5-fluorouracil cosubstrate: alpha-D-ribose-1-phosphate, enzyme from liver Rattus norvegicus
2.4.2.3 0.038
-
 alpha-D-ribose-1-phosphate cosubstrate: 5-fluorouracil, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.04
-
 alpha-D-ribose-1-phosphate cosubstrate: 5-fluorouracil, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.046
-
 5-fluorouracil cosubstrate: alpha-D-ribose-1-phosphate, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.06
-
 5-fluorouracil cosubstrate: alpha-D-ribose-1-phosphate, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.087
-
 alpha-D-ribose-1-phosphate cosubstrate: uracil, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.367
-
 Uracil cosubstrate: alpha-D-ribose-1-phosphate, enzyme from colon tumor Rattus norvegicus
2.4.2.3 0.485
-
 Uracil cosubstrate: alpha-D-ribose-1-phosphate, enzyme from liver Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.3 Gallus gallus
-
-
-
2.4.2.3 Homo sapiens
-
-
-
2.4.2.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.3 brain embryo Gallus gallus
-
2.4.2.3 breast cancer cell negative correlation between UPase expression and the clinical outcome of breast cancer Homo sapiens
-
2.4.2.3 colonic cancer cell
-
 Rattus norvegicus
-
2.4.2.3 colonic cancer cell RPMI Rattus norvegicus
-
2.4.2.3 embryo brain, liver and heart Gallus gallus
-
2.4.2.3 heart embryo Gallus gallus
-
2.4.2.3 liver
-
 Rattus norvegicus
-
2.4.2.3 liver embryo Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.3 5-fluorouracil + alpha-D-ribose-1-phosphate
-
 Homo sapiens 5-fluorouridine + phosphate
-
 ?
2.4.2.3 5-fluorouracil + alpha-D-ribose-1-phosphate
-
 Rattus norvegicus 5-fluorouridine + phosphate
-
 ?
2.4.2.3 uracil + alpha-D-ribose 1-phosphate
-
 Homo sapiens uridine + phosphate
-
 ?
2.4.2.3 uracil + alpha-D-ribose 1-phosphate
-
 Rattus norvegicus uridine + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.3 UPase
-
 Gallus gallus
2.4.2.3 UPase
-
 Homo sapiens
2.4.2.3 UPase
-
 Rattus norvegicus