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Literature summary extracted from

  • Karunakaran, R.; Ebert, K.; Harvey, S.; Leonard, M.E.; Ramachandran, V.; Poole, P.S.
    Thiamine is synthesized by a salvage pathway in Rhizobium leguminosarum bv. viciae strain 3841 (2006), J. Bacteriol., 188, 6661-6668.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.3 Escherichia coli
-
-
-
2.7.1.49 Rhizobium leguminosarum
-
 bv. viciae strain 3841
-
2.7.1.50 Rhizobium leguminosarum
-
 bv. viciae strain 3841
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.3 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)-thiazole
-
 Escherichia coli thiamine monophosphate + diphosphate
-
 ?
2.7.1.49 ATP + 2-methyl-4-amino-5-hydroxymethylpyrimidine
-
 Rhizobium leguminosarum ADP + 2-methyl-4-amino-5-phosphomethylpyrimidine
-
 ?
2.7.1.50 ATP + 4-methyl-5-(2-hydroxyethyl)thiazole
-
 Rhizobium leguminosarum ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.3 ThiL
-
 Escherichia coli
2.7.1.49 4-amino-5-hydroxymethyl-2-methyl pyrimidine kinase
-
 Rhizobium leguminosarum
2.7.1.49 HMP kinase
-
 Rhizobium leguminosarum
2.7.1.49 ThiD
-
 Rhizobium leguminosarum
2.7.1.50 4-methyl-5-(beta-hydroxyethyl) thiazole kinase
-
 Rhizobium leguminosarum
2.7.1.50 ThiM
-
 Rhizobium leguminosarum
2.7.1.50 THZ kinase
-
 Rhizobium leguminosarum

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.49 ATP
-
 Rhizobium leguminosarum
2.7.1.50 ATP
-
 Rhizobium leguminosarum