Literature summary extracted from

Pageau, K.; Reisdorf-Cren, M.; Morot-Gaudry, J.F.; Masclaux-Daubresse, C.
The two senescence-related markers, GS1 (cytosolic glutamine synthetase) and GDH (glutamate dehydrogenase), involved in nitrogen mobilization, are differentially regulated during pathogen attack and by stress hormones and reactive oxygen species in Nicotiana tabcum L. leaves (2006), J. Exp. Bot., 57, 547-557.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.4.1.2	ethylene	increase in the expression of GDH and the aminating GDH activity	Nicotiana tabacum
1.4.1.2	H2O2	increase in the aminating GDH activity correlating with gene expression, in a dose-dependent manner	Nicotiana tabacum
1.4.1.2	jasmonic acid	increase in the expression of GDH and the aminating GDH activity	Nicotiana tabacum
1.4.1.2	additional information	cryptogein and Onozuka R10 induce GDH expression, GDH activity is correlated with GDH expression and the GDH enzyme preferentially catalyses the aminating reaction	Nicotiana tabacum
1.4.1.2	additional information	GDH mRNA accumulates preferentially in plants inoculated with the avirulent Pseudomonas syringae pv. syringae CFBP3077 (hrp+) and the virulent Pseudomonas syringae pv. tabaci CFBP1503 strains, induction of GDH expression by bacterial infection dependeds on the hrp- genotype, but not on the virulence/avirulence genotype	Nicotiana tabacum
1.4.1.2	additional information	leaf GDH aminating-activity increases, whereas deaminating-activity is not affected by infection with viruses CMV, TEV, and PVY	Nicotiana tabacum
1.4.1.2	salicylic acid	increase in the expression of GDH	Nicotiana tabacum

Application

EC Number	Application	Comment	Organism
1.4.1.2	agriculture	GDH genes involved in leaf senescence are also a component of the plant defence response during plantpathogen interaction, GDH behaves like a non-specific stress-related gene	Nicotiana tabacum

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.4.1.2	Nicotiana tabacum	-	cv. Xanthi XHFD8 and cv. Xanthi G28	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.4.1.2	leaf	-	Nicotiana tabacum	-

Synonyms

EC Number	Synonyms	Comment	Organism
1.4.1.2	GDH	-	Nicotiana tabacum
1.4.1.2	glutamate dehydrogenase	-	Nicotiana tabacum

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Release 2023.1 (January 2023)