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Literature summary extracted from

  • Wang, L.; Jil, C.; Xu, Y.; Xu, J.; Dai, J.; Wu, Q.; Wu, M.; Zou, X.; Sun, L.; Gu, S.; Xie, Y.; Mao, Y.
    Cloning and characterization of a novel human homolog of mouse U26, a putative PQQ-dependent AAS dehydrogenase (2005), Mol. Biol. Rep., 32, 47-53.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.31 cDNA is cloned from a human fetal library, library is constructed in a modified pBluescript II SK+ vector, cDNA insert is sequenced Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.31 L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O Homo sapiens
-
 L-2-aminoadipate + NAD(P)H + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.31 Homo sapiens Q4L235
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.31 brain
-
 Homo sapiens
-
1.2.1.31 brain mRNA expression Homo sapiens
-
1.2.1.31 brain fetal brain cDNA library Homo sapiens
-
1.2.1.31 breast cancer cell
-
 Homo sapiens
-
1.2.1.31 colon
-
 Homo sapiens
-
1.2.1.31 colon mRNA expression Homo sapiens
-
1.2.1.31 colonic adenocarcinoma cell colon adenocarcinoma, CX-1 Homo sapiens
-
1.2.1.31 colonic adenocarcinoma cell colon adenocarcinoma, GI-112 Homo sapiens
-
1.2.1.31 heart
-
 Homo sapiens
-
1.2.1.31 heart mRNA expression Homo sapiens
-
1.2.1.31 kidney
-
 Homo sapiens
-
1.2.1.31 kidney high mRNA expression Homo sapiens
-
1.2.1.31 leukocyte peripheral blood leukocyte Homo sapiens
-
1.2.1.31 liver
-
 Homo sapiens
-
1.2.1.31 liver high mRNA expression Homo sapiens
-
1.2.1.31 lung
-
 Homo sapiens
-
1.2.1.31 lung mRNA expression Homo sapiens
-
1.2.1.31 lung cancer cell lung carcinoma, GI-117 Homo sapiens
-
1.2.1.31 lung cancer cell lung carcinoma, LX-1 Homo sapiens
-
1.2.1.31 ovary
-
 Homo sapiens
-
1.2.1.31 ovary mRNA expression Homo sapiens
-
1.2.1.31 ovary cancer cell ovarian carcinoma, GI-102 Homo sapiens
-
1.2.1.31 pancreas
-
 Homo sapiens
-
1.2.1.31 pancreas high mRNA expression Homo sapiens
-
1.2.1.31 peripheral blood mRNA expression Homo sapiens
-
1.2.1.31 placenta
-
 Homo sapiens
-
1.2.1.31 placenta mRNA expression Homo sapiens
-
1.2.1.31 prostate
-
 Homo sapiens
-
1.2.1.31 prostate adenocarcinoma cell prostatic adenocarcinoma, PC3 Homo sapiens
-
1.2.1.31 prostate gland mRNA expression Homo sapiens
-
1.2.1.31 skeletal muscle low mRNA expression Homo sapiens
-
1.2.1.31 skeletal system
-
 Homo sapiens
-
1.2.1.31 small intestine
-
 Homo sapiens
-
1.2.1.31 small intestine mRNA expression Homo sapiens
-
1.2.1.31 spleen
-
 Homo sapiens
-
1.2.1.31 spleen high mRNA expression Homo sapiens
-
1.2.1.31 testis
-
 Homo sapiens
-
1.2.1.31 testis high mRNA expression Homo sapiens
-
1.2.1.31 thymus
-
 Homo sapiens
-
1.2.1.31 thymus mRNA expression Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.31 L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O
-
 Homo sapiens L-2-aminoadipate + NAD(P)H + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.31 2-aminoadipic 6-semialdehyde dehydrogenase
-
 Homo sapiens
1.2.1.31 human U26
-
 Homo sapiens
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
-
 Homo sapiens
1.2.1.31 U26
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.31 pyrroloquinoline quinone PQQ Homo sapiens