EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.12 | 8-bromo-cGMP | PKG activator 8-bromo-cGMP abolishes thermoprotective effect of a prior heat shock | Drosophila melanogaster | |
2.7.11.12 | cGMP | - |
Drosophila melanogaster |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.11.12 | the enzyme is encoded by the foraging gene for which shows polymorphisms associated with the allelic variation in for | Drosophila melanogaster |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.12 | KT5823 | a specific PKG inhibitor, PKG inhibition induces rapid thermotolerance of neural circuitry | Drosophila melanogaster |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.12 | Mg2+ | - |
Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.12 | additional information | Drosophila melanogaster | reduced enzyme activity leads to increased thermotolerance of synaptic transmission at the larval neuromuscular junction, PKG and the for gene polymorphism associated with the allelic variation in for may provide populationswith natural variantion in heat stress tolerance, the for gene function in behaviour is conserved across most organisms, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.12 | Drosophila melanogaster | - |
gene for | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.12 | larva | - |
Drosophila melanogaster | - |
2.7.11.12 | muscle | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.12 | additional information | reduced enzyme activity leads to increased thermotolerance of synaptic transmission at the larval neuromuscular junction, PKG and the for gene polymorphism associated with the allelic variation in for may provide populationswith natural variantion in heat stress tolerance, the for gene function in behaviour is conserved across most organisms, overview | Drosophila melanogaster | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.12 | PKG | - |
Drosophila melanogaster |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.12 | ATP | - |
Drosophila melanogaster |