Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Brown, P.M.; Caradoc-Davies, T.T.; Dickson, J.M.; Cooper, G.J.; Loomes, K.M.; Baker, E.N.
    Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism (2006), Proc. Natl. Acad. Sci. USA, 103, 15032-15037.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.99.1 L-cysteine 2 mM Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.99.1 expressed in Escherichia coli Mus musculus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.13.99.1 crystals grow from a solution containing 20 mg/ml MIOX, 20 mM myo-inositol, 50 mM Mes pH 6.0, 50 mM NaCl, 2 mM Tris(2-carboxyethyl)-phosphine hydrochloride and 4.4 M sodium formate Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.99.1 Fe2+ 1 mM Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.13.99.1 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.13.99.1 Ni2+-affinity chromatography Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.99.1 kidney
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.99.1 D-chiro-inositol + O2
-
 Mus musculus ?
-
 ?
1.13.99.1 myo-inositol + O2
-
 Mus musculus D-glucuronate + H2O
-
 ir

Subunits

EC Number Subunits Comment Organism
1.13.99.1 monomer x-ray crystallography Mus musculus

Synonyms

EC Number Synonyms Comment Organism
1.13.99.1 MIOX
-
 Mus musculus
1.13.99.1 Myo-inositol oxygenase
-
 Mus musculus