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Literature summary extracted from

  • Anagli, J.; Abounit, K.; Stemmer, P.; Han, Y.; Allred, L.; Weinsheimer, S.; Movsisyan, A.; Seyfried, D.
    Effects of cathepsins B and L inhibition on postischemic protein alterations in the brain (2008), Biochem. Biophys. Res. Commun., 366, 86-91.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.1 CBZ-Phe-Ser(OBzl)-CHN2 cysteine protease inhibitor 1 (CP-1), effective inhibition at 0.05 mM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Rattus norvegicus P00787
-
-
3.4.22.15 Rattus norvegicus P07154
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.1 brain
-
 Rattus norvegicus
-
3.4.22.15 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.1 benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
-
 Rattus norvegicus benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.22.1 CatB
-
 Rattus norvegicus