Literature summary extracted from

Consonni, R.; Santomo, L.; Fusi, P.; Tortora, P.; Zetta, L.
A single-point mutation in the extreme heat- and pressure-resistant sso7d protein from Sulfolobus solfataricus leads to a major rearrangement of the hydrophobic core (1999), Biochemistry, 38, 12709-12717.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
4.6.1.18	determination of solution structure of mutant F31A by NMR spectroscopy reveals the change in orientation of the W23 side chain, which in the wild type is completely exposed to the solvent, whereas in the mutant is largely buried in the aromatic cluster. Mutation leads to strong distortion in the alpha-sheets with loss in several hydrogen bonds, and increased flexibility of some stretches of the backbone	Saccharolobus solfataricus

Protein Variants

EC Number	Protein Variants	Comment	Organism
4.6.1.18	F31A	loss in thermo and piezostabilities by at least 27 K and 10 kbar. Determination of solution structure by NMR spectroscopy reveals the change in orientation of the W23 side chain, which in the wild type is completely exposed to the solvent, whereas in the mutant is largely buried in the aromatic cluster. Mutation leads to strong distortion in the alpha-sheets with loss in several hydrogen bonds, and increased flexibility of some stretches of the backbone	Saccharolobus solfataricus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.6.1.18	Saccharolobus solfataricus	P61991	-	-

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Release 2023.1 (January 2023)