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Literature summary extracted from

  • Lang, I.; Goebel, C.; Porzel, A.; Heilmann, I.; Feussner, I.
    A lipoxygenase with linoleate diol synthase activity from Nostoc sp. PCC 7120 (2008), Biochem. J., 410, 347-357.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.61 expression of separate domains of NspLOX and the entire protein in Escherichia coli Nostoc sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.13.11.61 70900
-
 x * 70900, calculated from sequence Nostoc sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.61 alpha-linolenate + O2 Nostoc sp. i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 alpha-linolenate + O2 Nostoc sp. PCC 7120 i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 linoleate + O2 Nostoc sp. the enzyme is involved in oxylipin biosyntesis (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?
1.13.11.61 linoleate + O2 Nostoc sp. PCC 7120 the enzyme is involved in oxylipin biosyntesis (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.B1 Nostoc sp. Q8YK97 strain PCC 7120
-
1.13.11.61 Nostoc sp.
-
-
-
1.13.11.61 Nostoc sp. PCC 7120
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.B1 alpha-linolenic acid + O2 preferred substrate Nostoc sp. (10E,12E,14E)-9,16-dihydroxy-10,12,14-octadecatrienoic acid
-
 ?
1.13.11.B1 linoleic acid + O2
-
 Nostoc sp. (10E,12E)-9,14-dihydroxy-10,12-octadecadienoic acid
-
 ?
1.13.11.61 alpha-linolenate + O2 i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate Nostoc sp. (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 alpha-linolenate + O2 i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate. Preferred substrate Nostoc sp. (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 alpha-linolenate + O2 i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate Nostoc sp. PCC 7120 (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 alpha-linolenate + O2 i.e. (9Z,12Z,15Z)-octadeca-9,12,15-trienoate. Preferred substrate Nostoc sp. PCC 7120 (9R,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
-
 ?
1.13.11.61 linoleate + O2 the enzyme is involved in oxylipin biosyntesis Nostoc sp. (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?
1.13.11.61 linoleate + O2 i.e. (9Z,12Z)-octadeca-9,12-dienoate, the C-terminal portion of NspLOX is identified as a linoleate linoleate (9R)-lipoxygenase. 42% of the activity with alpha-linolenic acid Nostoc sp. (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?
1.13.11.61 linoleate + O2 the enzyme is involved in oxylipin biosyntesis Nostoc sp. PCC 7120 (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?
1.13.11.61 linoleate + O2 i.e. (9Z,12Z)-octadeca-9,12-dienoate, the C-terminal portion of NspLOX is identified as a linoleate linoleate (9R)-lipoxygenase. 42% of the activity with alpha-linolenic acid Nostoc sp. PCC 7120 (9R,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.61 ? x * 70900, calculated from sequence Nostoc sp.

Synonyms

EC Number Synonyms Comment Organism
1.13.11.61 (9R)-LOX
-
 Nostoc sp.
1.13.11.61 NspLOX NspLOX C-terminal portion exhibits activity as a inoleate 9R-lipoxygenase Nostoc sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.13.11.B1 7 10
-
 Nostoc sp.
1.13.11.61 7 10 broad pH-optimum Nostoc sp.