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Literature summary extracted from

  • Todorova, D.; Vaseva, I.; Malbeck, J.; Travnickova, A.; Machackova, I.; Karanov, E.
    Cytokinin oxidase/dehydrogenase activity as a tool in gibberellic acid/cytokinin cross talk (2007), Biol. Plant., 51, 579-583.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.5.99.12 additional information cultivation in the presence of gibberillic acid increases enzyme activity in leaves of cv. Scinado Pisum sativum

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.99.12 additional information cultivation in the presence of gibberillic acid reduces enzyme activity in leaves of cv. Manuela Pisum sativum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.99.12 additional information Pisum sativum irreversible oxidative cleavage of the N6-side chain of cytokinins, products are adenine and side-chain derived aldehyde, results suggest that CKX is responsible for the changes in endogenous cytokinin pool in gibberellic acid-treated plants and most probably this enzyme represents an important link in gibberellic acid/cytokinin cross talk ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.99.12 Pisum sativum A0MQ40 L. cv. Scinado and cv. Manuela, cv. Scinado normally requires shorter growing period than cv. Manuela
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.99.12 leaf lower CK content and higher enzymatic activity in cv. Manuela leaves compared with cv. Scinado Pisum sativum
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1.5.99.12 root cv. Manuela has a higher endogenous cytokinin content and slightly lower enzyme activity than cv. Scinado Pisum sativum
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.99.12 additional information irreversible oxidative cleavage of the N6-side chain of cytokinins, products are adenine and side-chain derived aldehyde, results suggest that CKX is responsible for the changes in endogenous cytokinin pool in gibberellic acid-treated plants and most probably this enzyme represents an important link in gibberellic acid/cytokinin cross talk Pisum sativum ?
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 ?
1.5.99.12 N6-isopentenyladenine + CuCl2
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 Pisum sativum adenine + 3-methyl-2-butenal + reduced electron acceptor
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 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.99.12 CKX
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 Pisum sativum
1.5.99.12 cytokinin oxidase/dehydrogenase
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 Pisum sativum

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.99.12 FAD
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 Pisum sativum