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Literature summary extracted from

  • Bao, X.; Tian, X.; Zhao, Z.; Qu, Y.; Wang, B.; Zhang, J.; Liu, T.; Yang, L.; Lv, J.; Song, C.
    Immunohistochemical evidence for the presence of tryptophan hydroxylase in the brains of insects as revealed by sheep anti-tryptophan hydroxylase polyclonal antibody (2008), Cell Tissue Res., 332, 555-563.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Drosophila melanogaster
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Blattella germanica
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Harmonia axyridis
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Childrena zenobia
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Camponotus japonicus
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2 Antheraea pernyi
-
5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.4 Antheraea pernyi
-
-
-
1.14.16.4 Blattella germanica
-
-
-
1.14.16.4 Camponotus japonicus
-
-
-
1.14.16.4 Childrena zenobia
-
-
-
1.14.16.4 Drosophila melanogaster
-
-
-
1.14.16.4 Harmonia axyridis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Drosophila melanogaster
-
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Blattella germanica
-
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Harmonia axyridis
-
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Childrena zenobia
-
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Camponotus japonicus
-
1.14.16.4 brain immunohistochemic analysis for TPH-like reactivity, neuronal distribution, overview Antheraea pernyi
-
1.14.16.4 head
-
Drosophila melanogaster
-
1.14.16.4 head
-
Blattella germanica
-
1.14.16.4 head
-
Harmonia axyridis
-
1.14.16.4 head
-
Childrena zenobia
-
1.14.16.4 head
-
Camponotus japonicus
-
1.14.16.4 head
-
Antheraea pernyi
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Drosophila melanogaster
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Blattella germanica
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Harmonia axyridis
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Childrena zenobia
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Camponotus japonicus
-
1.14.16.4 additional information enzyme distribution between optic lobe and protocerebrum, dorsal protocerebrum, deutocerebrum, and subesophageal ganglion, overview Antheraea pernyi
-
1.14.16.4 neuron
-
Drosophila melanogaster
-
1.14.16.4 neuron
-
Blattella germanica
-
1.14.16.4 neuron
-
Harmonia axyridis
-
1.14.16.4 neuron
-
Childrena zenobia
-
1.14.16.4 neuron
-
Camponotus japonicus
-
1.14.16.4 neuron
-
Antheraea pernyi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Drosophila melanogaster 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Blattella germanica 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Harmonia axyridis 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Childrena zenobia 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Camponotus japonicus 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?
1.14.16.4 L-tryptophan + tetrahydrobiopterin + O2
-
Antheraea pernyi 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.16.4 TPH
-
Drosophila melanogaster
1.14.16.4 TPH
-
Blattella germanica
1.14.16.4 TPH
-
Harmonia axyridis
1.14.16.4 TPH
-
Childrena zenobia
1.14.16.4 TPH
-
Camponotus japonicus
1.14.16.4 TPH
-
Antheraea pernyi
1.14.16.4 tryptophan hydroxylase
-
Drosophila melanogaster
1.14.16.4 tryptophan hydroxylase
-
Blattella germanica
1.14.16.4 tryptophan hydroxylase
-
Harmonia axyridis
1.14.16.4 tryptophan hydroxylase
-
Childrena zenobia
1.14.16.4 tryptophan hydroxylase
-
Camponotus japonicus
1.14.16.4 tryptophan hydroxylase
-
Antheraea pernyi