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Literature summary extracted from
- Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans (2008), FEMS Microbiol. Lett., 286, 66-70.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.11.1.7 | medicine | QPO is a potential drug target to inhibit the expression of leukotoxin LtxA from Aggregatibacter actinomycetemcomitans for the treatment and prevention of localized aggressive periodontitis | Aggregatibacter actinomycetemcomitans |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.11.1.7 | additional information | the QPO null mutant shows an oxidative stress phenotype, suggesting that QPO plays a certain role in scavenging endogenously generated reactive oxygen species | Aggregatibacter actinomycetemcomitans |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.7 | 53600 | - |
SDS-PAGE | Aggregatibacter actinomycetemcomitans |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.7 | Aggregatibacter actinomycetemcomitans | A2A1C5 | - |
- |
| 1.11.1.7 | Aggregatibacter actinomycetemcomitans IDH781 | A2A1C5 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.7 | additional information | QPO catalyzes the reduction of H2O2 but not tert-butyl hydroperoxide and cumene hydroperoxide | Aggregatibacter actinomycetemcomitans | ? | - |
? |  |
| 1.11.1.7 | additional information | QPO catalyzes the reduction of H2O2 but not tert-butyl hydroperoxide and cumene hydroperoxide | Aggregatibacter actinomycetemcomitans IDH781 | ? | - |
? | |
| 1.11.1.7 | ubiquinol-1 + H2O2 | - |
Aggregatibacter actinomycetemcomitans | ? + H2O | - |
? | |
| 1.11.1.7 | ubiquinol-1 + H2O2 | - |
Aggregatibacter actinomycetemcomitans IDH781 | ? + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.11.1.7 | QPO | - |
Aggregatibacter actinomycetemcomitans |
| 1.11.1.7 | quinol peroxidase | - |
Aggregatibacter actinomycetemcomitans |
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Release 2023.1 (January 2023)
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