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Literature summary extracted from

  • Masuda, T.; Odaka, Y.; Ogawa, N.; Nakamoto, K.; Kuninaga, H.
    Identification of geranic acid, a tyrosinase inhibitor in lemongrass (Cymbopogon citratus) (2008), J. Agric. Food Chem., 56, 597-601.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 3-methylcrotonic acid
-
 Agaricus bisporus
1.14.18.1 angelic acid
-
 Agaricus bisporus
1.14.18.1 crotonic acid
-
 Agaricus bisporus
1.14.18.1 farnesic acid
-
 Agaricus bisporus
1.14.18.1 geranial
-
 Agaricus bisporus
1.14.18.1 geranic acid in lemongrass (Cymbopogon citratus) Agaricus bisporus
1.14.18.1 geranic acid ethyl amide
-
 Agaricus bisporus
1.14.18.1 geranic acid ethyl ester
-
 Agaricus bisporus
1.14.18.1 geranic acid ethylene glycol ester
-
 Agaricus bisporus
1.14.18.1 geraniol
-
 Agaricus bisporus
1.14.18.1 isovaleric acid
-
 Agaricus bisporus
1.14.18.1 Methacrylic acid
-
 Agaricus bisporus
1.14.18.1 tiglic acid
-
 Agaricus bisporus
1.14.18.1 trans-geranic acid
-
 Agaricus bisporus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.18.1 commercial preparation
-
 Agaricus bisporus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 L-dopa + 1/2 O2
-
 Agaricus bisporus L-dopaquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 tyrosinase
-
 Agaricus bisporus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.18.1 0.11
-
-
 Agaricus bisporus farnesic acid
1.14.18.1 0.14
-
 isomer 1 Agaricus bisporus trans-geranic acid
1.14.18.1 1.62
-
-
 Agaricus bisporus geranial
1.14.18.1 1.7
-
-
 Agaricus bisporus 3-methylcrotonic acid
1.14.18.1 2.3
-
 isomer 2 Agaricus bisporus trans-geranic acid