EC Number | Cloned (Comment) | Organism |
---|---|---|
1.3.5.1 | gene SDHB ecoding the subunit B, genotype-phenotype correlations among patients with SDHB mutations in different exons do not reveal obvious differences for age at presentation, biochemical phenotype, primary tumor size and location, distribution of metastatic lesions, or presence of additional head and neck paragangliomas, overview | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.3.5.1 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.5.1 | additional information | Homo sapiens | germline mutations of the gene SDHB encoding succinate dehydrogenase subunit B predispose to malignant paraganglioma. Despite an autosomal dominant pattern of inheritance, penetrance of the disease is incomplete and age dependent, overview | ? | - |
? | |
1.3.5.1 | succinate + ubiquinone | Homo sapiens | - |
fumarate + ubiquinol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.5.1 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.5.1 | additional information | germline mutations of the gene SDHB encoding succinate dehydrogenase subunit B predispose to malignant paraganglioma. Despite an autosomal dominant pattern of inheritance, penetrance of the disease is incomplete and age dependent, overview | Homo sapiens | ? | - |
? | |
1.3.5.1 | succinate + ubiquinone | - |
Homo sapiens | fumarate + ubiquinol | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.5.1 | SDH | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.5.1 | ubiquinone | - |
Homo sapiens |