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Literature summary extracted from

  • Morett, E.; Saab-Rincon, G.; Olvera, L.; Olvera, M.; Flores, H.; Grande, R.
    Sensitive genome-wide screen for low secondary enzymatic activities: the YjbQ family shows thiamin phosphate synthase activity (2008), J. Mol. Biol., 376, 839-853.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.3 expression in Escherichia coli Escherichia coli
2.5.1.3 overexpression of YjbQ complements the thiamin auxotrophy of the Escherichia coli MC1061DELTAthiE strain, in spite of their thiamine phosphate synthase activity being several orders of magnitude lower than that of the thiE-coded enzyme Pyrococcus furiosus
2.5.1.3 overexpression of YjbQ complements the thiamin auxotrophy of the Escherichia coli MC1061DELTAthiE strain, in spite of their thiamine phosphate synthase activity being several orders of magnitude lower than that of the thiE-coded enzyme Thermotoga maritima
2.5.1.3 overexpression of YjbQ complements the thiamin auxotrophy of the Escherichia coli MC1061DELTAthiE strain, in spite of their thiamine phosphate synthase activity being several orders of magnitude lower than that of the thiE-coded enzyme Saccharolobus solfataricus

Protein Variants

EC Number Protein Variants Comment Organism
2.5.1.3 additional information in enzyme deletion mutant, no growth difference is observed when compared to the wild-type strain Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.3 Escherichia coli
-
-
-
2.5.1.3 Pyrococcus furiosus Q8U3C6
-
-
2.5.1.3 Saccharolobus solfataricus Q97VS8
-
-
2.5.1.3 Saccharolobus solfataricus P2 Q97VS8
-
-
2.5.1.3 Thermotoga maritima Q9WZI2
-
-
2.5.1.3 Thermotoga maritima Q9X2I5
-
-
2.5.1.3 Thermotoga maritima DSM 3109 Q9WZI2
-
-
2.5.1.3 Thermotoga maritima DSM 3109 Q9X2I5
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.3 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)-thiazole very low activity, almost 400-fold lower than the activity shown by the thiE-encoded thiamine-phosphate diphosphatase of Escherichia coli Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.3 PF0544 locus name Pyrococcus furiosus
2.5.1.3 SSO2532 locus name Saccharolobus solfataricus
2.5.1.3 thiamin phosphate synthase
-
 Pyrococcus furiosus
2.5.1.3 thiamin phosphate synthase
-
 Thermotoga maritima
2.5.1.3 thiamin phosphate synthase
-
 Saccharolobus solfataricus
2.5.1.3 TM0723 locus name Thermotoga maritima
2.5.1.3 TM1872 locus name Thermotoga maritima
2.5.1.3 YjbQ
-
 Pyrococcus furiosus
2.5.1.3 YjbQ
-
 Thermotoga maritima
2.5.1.3 YjbQ
-
 Saccharolobus solfataricus