EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.17.3.2 | allopurinol | - |
Rattus norvegicus | |
1.17.3.2 | febuxostat | the inhibitor lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.3.2 | xanthine + H2O + O2 | Rattus norvegicus | xanthine oxidase inhibition by febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in hyperuricaemia, experimentally-induced by inhibition of uricase with oxonic acid, overview | urate + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.3.2 | Rattus norvegicus | - |
male sprague-dawley rats | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.17.3.2 | kidney | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.3.2 | xanthine + H2O + O2 | production of superoxide radicals | Rattus norvegicus | urate + H2O2 | - |
? | |
1.17.3.2 | xanthine + H2O + O2 | xanthine oxidase inhibition by febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in hyperuricaemia, experimentally-induced by inhibition of uricase with oxonic acid, overview | Rattus norvegicus | urate + H2O2 | - |
? |