EC Number | Cloned (Comment) | Organism |
---|---|---|
6.3.4.3 | expressed in CHO cells and Escherichia coli | Homo sapiens |
6.3.4.3 | expressed in CHO cells and Escherichia coli | Rattus norvegicus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
6.3.4.3 | additional information | the recombinant protein product (short isoform) of the alternatively spliced short transcript of the mitochondrial isozyme is not enzymatically active | Homo sapiens |
6.3.4.3 | additional information | the recombinant protein product (short isoform) of the alternatively spliced short transcript of the mitochondrial isozyme is not enzymatically active | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.3.4.3 | mitochondrion | mitochondrial C1-THF synthase behaves as a peripheral membrane protein, tightly associated with the matrix side of the mitochondrial inner membrane | Homo sapiens | 5739 | - |
6.3.4.3 | mitochondrion | mitochondrial C1-THF synthase behaves as a peripheral membrane protein, tightly associated with the matrix side of the mitochondrial inner membrane | Rattus norvegicus | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.4.3 | 35000 | - |
recombinant short isoform, SDS-PAGE | Homo sapiens |
6.3.4.3 | 107000 | - |
recombinant mitochondrial C1-THF synthase without the presequence but with the V5 epitope tag, SDS-PAGE | Homo sapiens |
6.3.4.3 | 107000 | - |
recombinant mitochondrial C1-THF synthase without the presequence but with the V5 epitope tag, SDS-PAGE | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.3 | Homo sapiens | - |
- |
- |
6.3.4.3 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.4.3 | TALON cobalt metal affinity resin chromatography | Homo sapiens |
6.3.4.3 | TALON cobalt metal affinity resin chromatography | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.4.3 | placenta | - |
Homo sapiens | - |
6.3.4.3 | spleen | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.3 | ATP + formate + tetrahydrofolate | - |
Homo sapiens | ADP + phosphate + 10-formyltetrahydrofolate | - |
? | |
6.3.4.3 | ATP + formate + tetrahydrofolate | - |
Rattus norvegicus | ADP + phosphate + 10-formyltetrahydrofolate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.3.4.3 | C(1)-tetrahydrofolate synthase | a monofunctional 10-formyl-tetrahydrofolate synthetase lacking the 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methenyl-tetrahydrofolate cyclohydrolase activities typically found in the trifunctional cytoplasmic proteins | Homo sapiens |
6.3.4.3 | C(1)-tetrahydrofolate synthase | a monofunctional 10-formyl-tetrahydrofolate synthetase lacking the 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methenyl-tetrahydrofolate cyclohydrolase activities typically found in the trifunctional cytoplasmic proteins | Rattus norvegicus |
6.3.4.3 | MTHFDIL | - |
Homo sapiens |
6.3.4.3 | MTHFDIL | - |
Rattus norvegicus |
6.3.4.3 | THF synthase | - |
Homo sapiens |
6.3.4.3 | THF synthase | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.3 | ATP | - |
Homo sapiens | |
6.3.4.3 | ATP | - |
Rattus norvegicus |