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Literature summary extracted from

  • Ueno, K.; Kidokoro, Y.
    Adenylyl cyclase encoded by AC78C participates in sugar perception in Drosophila melanogaster (2008), Eur. J. Neurosci., 28, 1956-1966.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.6.1.1 additional information RNAi against gene AC78C, but not against gene ACXE, depressed the sucrose response in gustatory receptor neurons Drosophila melanogaster

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.1 MDL-12330A the adenylate cyclase inhibitor depresses the response in GRNs to trehalose as well as sucrose in gustatory receptor neurons Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.1 ATP Drosophila melanogaster the enzyme, via cAMP, participates in the sugar-taste signaling pathway at the low concentration range, the long form of AC78C product is essential for the normal sugar response in adult flies, overview 3',5'-cyclic-AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Drosophila melanogaster
-
 gene AC78C
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.1 neuron gustatory receptor neurons Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.1 ATP
-
 Drosophila melanogaster 3',5'-cyclic-AMP + diphosphate
-
 ?
4.6.1.1 ATP the enzyme, via cAMP, participates in the sugar-taste signaling pathway at the low concentration range, the long form of AC78C product is essential for the normal sugar response in adult flies, overview Drosophila melanogaster 3',5'-cyclic-AMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 adenylyl cyclase
-
 Drosophila melanogaster