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Literature summary extracted from

  • Sasaki, N.; Egashira, Y.; Sanada, H.
    Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha (2008), Eur. J. Nutr., 47, 80-86.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.45 eicosapentaenoic acid ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of eicosapentaenoic acid Rattus norvegicus
4.1.1.45 linoleic acid ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of linoleic acid Rattus norvegicus
4.1.1.45 additional information MK886 does not influence the suppressive effects of polyunsaturated fatty acids on ACMSD activity Rattus norvegicus
4.1.1.45 WY-14,643 ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of WY-14,643 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.45 additional information Rattus norvegicus key enzyme in NAD biosynthesis from tryptophan ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.45 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.45 hepatocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.45 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
-
 Rattus norvegicus 2-aminomuconate semialdehyde + CO2
-
 ?
4.1.1.45 additional information key enzyme in NAD biosynthesis from tryptophan Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.45 ACMSD
-
 Rattus norvegicus
4.1.1.45 alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
-
 Rattus norvegicus