Literature summary extracted from

Mikkelsen, N.E.; Munch-Petersen, B.; Eklund, H.
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (2008), FEBS J., 275, 2151-2160.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.7.1.145	in complex with floxuridine, brivudine, zidovudine, zalcitabine, or dCTP or dGTP with resolution of 2.2-2.9 A. dCTP and dGTP bind with the base in the substrate site, similarly to feedback inhibitor dTTP. Contrary to nucleoside analogs, dGTP adopts a syn conformation	Drosophila melanogaster

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.145	Drosophila melanogaster	Q9XZT6	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)