EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.2 | BAY 41-2272 | allosteric activator | Bos taurus | |
4.6.1.2 | CO | - |
Bos taurus | |
4.6.1.2 | NO | about 5000fold activation over basal level, mechanism for NO receptor activation and its modulation by GTP, ATP, and allosteric agents, model formation comprising a module in which NO, the nucleotides, and allosteric agents bind and the protein undergoes a conformational change, dovetailing with a catalytic module where GTP is converted to cGMP and diphosphate, enzyme-linked receptor mechanism, overview | Bos taurus | |
4.6.1.2 | YC-1 | allosteric activator | Bos taurus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.2 | ATP | inhibition by ATP of GC activity stimulated by NO | Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.6.1.2 | additional information | - |
additional information | activation kinetics and thermodynamics, binding of GTP and NO, overview | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.2 | GTP | Bos taurus | - |
3',5'-cyclic GMP + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.2 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.6.1.2 | from lung | Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.6.1.2 | lung | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.2 | GTP | - |
Bos taurus | 3',5'-cyclic GMP + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.2 | soluble guanylyl cyclase | - |
Bos taurus |