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Literature summary extracted from

  • Berlicki, L.
    Inhibitors of glutamine synthetase and their potential application in medicine (2008), Mini Rev. Med. Chem., 8, 869-878.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.1.2 (1,4-diamino-4-oxobutyl)phosphonic acid
-
 Rattus norvegicus
6.3.1.2 (1-amino-4-methoxy-4-oxobutyl)phosphonic acid
-
 Rattus norvegicus
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Escherichia coli
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Ovis aries
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Sorghum sp.
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Spinacia oleracea
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Vigna radiata
6.3.1.2 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclopentanecarboxylic acid racemic mixture Vigna radiata
6.3.1.2 (2R,3S)-3-aminooxetane-2-carboxylic acid
-
 Bacillus subtilis
6.3.1.2 (2R,3S)-3-aminooxetane-2-carboxylic acid
-
 Spinacia oleracea
6.3.1.2 (2S)-2-amino-4-(hydroxyamino)butanoic acid
-
 Bradyrhizobium japonicum
6.3.1.2 (2S)-2-amino-4-(hydroxyamino)butanoic acid
-
 Ovis aries
6.3.1.2 (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 (2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 (2S)-2-amino-4-[(3S)-3-hydroxy-2-oxoazetidin-3-yl]butanoic acid irrversible Pisum sativum
6.3.1.2 (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 (2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid
-
 Mus musculus
6.3.1.2 (3,4-diamino-4-oxobutyl)methylphosphinic acid
-
 Rattus norvegicus
6.3.1.2 (3-amino-4-methoxy-4-oxobutyl)methylphosphinic acid
-
 Rattus norvegicus
6.3.1.2 (R)-methionine sulfoximine phosphate weak inhibition compared to the S-enantiomer Escherichia coli
6.3.1.2 (R)-methionine sulfoximine phosphate weak inhibition compared to the S-enantiomer Mycobacterium tuberculosis
6.3.1.2 (R)-methionine sulfoximine phosphate weak inhibition compared to the S-enantiomer Ovis aries
6.3.1.2 (R)-methionine sulfoximine phosphate weak inhibition compared to the S-enantiomer Pisum sativum
6.3.1.2 (R)-methionine sulfoximine phosphate weak inhibition compared to the S-enantiomer Spinacia oleracea
6.3.1.2 (S)-methionine sulfoximine phosphate irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated Escherichia coli
6.3.1.2 (S)-methionine sulfoximine phosphate irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated Mycobacterium tuberculosis
6.3.1.2 (S)-methionine sulfoximine phosphate irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated Ovis aries
6.3.1.2 (S)-methionine sulfoximine phosphate irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated Pisum sativum
6.3.1.2 (S)-methionine sulfoximine phosphate irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated Spinacia oleracea
6.3.1.2 ([[2-(4-hydroxyphenyl)ethyl]amino]methanediyl)bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 2-amino-2-ethyl-4-(S-methylsulfonimidoyl)butanoic acid 41% inhibition at 0.4 mM Escherichia coli
6.3.1.2 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Ovis aries
6.3.1.2 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Sorghum sp.
6.3.1.2 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 2-amino-4-(S-ethylsulfonimidoyl)butanoic acid 76.4% inhibition at 10 mM Escherichia coli
6.3.1.2 2-amino-4-(S-propylsulfonimidoyl)butanoic acid 35.8% inhibition at 20 mM Escherichia coli
6.3.1.2 2-amino-4-hydroxyglutaric acid
-
 Chlorella sp.
6.3.1.2 2-amino-4-[(3,4-dichlorobenzyl)(hydroxy)phosphoryl]butanoic acid 20% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[(3,5-dimethylbenzyl)(hydroxy)phosphoryl]butanoic acid 20% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[(4-bromobenzyl)(hydroxy)phosphoryl]butanoic acid 20% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[(carboxymethyl)(hydroxy)phosphoryl]butanoic acid 20% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid
-
 Ovis aries
6.3.1.2 2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid 51% inhibition at 0.5 mM Spinacia oleracea
6.3.1.2 2-amino-4-[benzyl(hydroxy)phosphoryl]butanoic acid 30% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid
-
 Columba sp.
6.3.1.2 2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 2-amino-4-[hydroxy(oxido)phosphanyl]butanoic acid 35% inhibition at 12.5 mM Pisum sativum
6.3.1.2 2-amino-4-[hydroxy(phenyl)phosphoryl]butanoic acid 30% inhibition at 0.5 mM Columba sp.
6.3.1.2 2-amino-4-[hydroxy(phosphonomethyl)amino]butanoic acid 50% inhibition at 0.5 mM Spinacia oleracea
6.3.1.2 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Ovis aries
6.3.1.2 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 2-amino-4-[methyl(phosphonomethyl)amino]butanoic acid 29% inhibition at 0.5 mM Spinacia oleracea
6.3.1.2 2-amino-4-[methyl(phosphonomethyl)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 2-[(diphosphonomethyl)amino]pyridine-3-carboxylic acid
-
 Oryza sativa
6.3.1.2 3-amino-5-[hydroxy(methyl)phosphoryl]tetrahydrofuran-3-carboxylic acid
-
 Vigna radiata
6.3.1.2 3-[(diphosphonomethyl)amino]benzoic acid
-
 Oryza sativa
6.3.1.2 3-[(phosphonoacetyl)amino]alanine
-
 Escherichia coli
6.3.1.2 3-[(phosphonoacetyl)amino]alanine
-
 Pisum sativum
6.3.1.2 4-(S-ethylsulfonimidoyl)isovaline 25.8% inhibition at 2 mM Escherichia coli
6.3.1.2 4-(S-methylsulfonimidoyl)isovaline 80% inhibition at 0.1 mM Escherichia coli
6.3.1.2 4-(S-propylsulfonimidoyl)isovaline 34.6% inhibition at 20 mM Escherichia coli
6.3.1.2 4-amino-4-phosphonobutanoic acid
-
 Rattus norvegicus
6.3.1.2 4-amino-4-phosphonopentanoic acid
-
 Rattus norvegicus
6.3.1.2 4-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Rattus norvegicus
6.3.1.2 4-amino-4-[hydroxy(methyl)phosphoryl]pentanoic acid
-
 Rattus norvegicus
6.3.1.2 4-fluoroglutamic acid
-
 Chlorella sp.
6.3.1.2 4-phosphonohomoserine
-
 Escherichia coli
6.3.1.2 4-phosphonohomoserine
-
 Ovis aries
6.3.1.2 4-phosphonohomoserine
-
 Sorghum sp.
6.3.1.2 4-phosphonohomoserine
-
 Spinacia oleracea
6.3.1.2 4-phosphonohomoserine
-
 Vigna radiata
6.3.1.2 4-phosphonoisovaline
-
 Rattus norvegicus
6.3.1.2 4-phosphononorvaline
-
 Escherichia coli
6.3.1.2 4-phosphononorvaline
-
 Ovis aries
6.3.1.2 4-phosphononorvaline
-
 Sorghum sp.
6.3.1.2 4-phosphononorvaline
-
 Spinacia oleracea
6.3.1.2 4-phosphononorvaline
-
 Vigna radiata
6.3.1.2 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Escherichia coli
6.3.1.2 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Ovis aries
6.3.1.2 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Rattus norvegicus
6.3.1.2 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Sorghum sp.
6.3.1.2 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Spinacia oleracea
6.3.1.2 5-oxo-6-phosphononorleucine
-
 Escherichia coli
6.3.1.2 5-oxo-6-phosphononorleucine
-
 Ovis aries
6.3.1.2 5-oxo-6-phosphononorleucine
-
 Pisum sativum
6.3.1.2 5-oxolysine
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 5-oxolysine isozyme GS1; isozyme GS2 Zea mays
6.3.1.2 5-[(3-amino-3-carboxypropyl)(hydroxy)phosphoryl]norvaline 20% inhibition at 12.5 mM Pisum sativum
6.3.1.2 D,L-phosphinothricin
-
 Oryza sativa
6.3.1.2 L-glutamyl gamma-phosphinic acid
-
 Columba sp.
6.3.1.2 L-glutamyl gamma-phosphinic acid
-
 Escherichia coli
6.3.1.2 methionine sulfone
-
 Escherichia coli
6.3.1.2 methionine sulfone amine
-
 Escherichia coli
6.3.1.2 methionine sulfoxide
-
 Escherichia coli
6.3.1.2 methionine sulfoximine
-
 Ovis aries
6.3.1.2 methionine sulfoximine
-
 Pisum sativum
6.3.1.2 methionine sulfoximine
-
 Spinacia oleracea
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Bacillus subtilis
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Beta vulgaris
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Bradyrhizobium japonicum
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Chlorella sp.
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Columba sp.
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Escherichia coli
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Homo sapiens
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview; structure-activity relationships and inhibitor design, overview Hordeum vulgare
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Mus musculus
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Mycobacterium tuberculosis
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Oryza sativa
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Ovis aries
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Pisum sativum
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Rattus norvegicus
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Senna obtusifolia
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Sorghum sp.
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Spinacia oleracea
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Synechocystis sp.
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Triticum aestivum
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Vigna radiata
6.3.1.2 additional information structure-activity relationships and inhibitor design, overview Zea mays
6.3.1.2 O-acetyl-4-phosphonohomoserine
-
 Escherichia coli
6.3.1.2 O-acetyl-4-phosphonohomoserine
-
 Sorghum sp.
6.3.1.2 P-ethyl gamma-phosphinic L-glutamate
-
 Columba sp.
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Beta vulgaris
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Bradyrhizobium japonicum
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Escherichia coli
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes; isolated from Streptomyces viridochromogenes Hordeum vulgare
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Ovis aries
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Pisum sativum
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Rattus norvegicus
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Senna obtusifolia
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Sorghum sp.
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Spinacia oleracea
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Triticum aestivum
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Vigna radiata
6.3.1.2 Phosphinothricin isolated from Streptomyces viridochromogenes Zea mays
6.3.1.2 [(cyclohexylamino)methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [(pyridin-2-ylamino)methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [1-amino-3-(S-methylsulfonimidoyl)propyl]phosphonic acid
-
 Escherichia coli
6.3.1.2 [[(3,5-dichlorophenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [[(3-nitrophenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [[(4-methylphenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [[(5-chloropyridin-2-yl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 [[(pyridin-2-ylmethyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.1.2 chloroplast
-
 Spinacia oleracea 9507
-
6.3.1.2 cytosol
-
 Spinacia oleracea 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.1.2 Mg2+
-
 Beta vulgaris
6.3.1.2 Mg2+
-
 Escherichia coli
6.3.1.2 Mg2+
-
 Triticum aestivum
6.3.1.2 Mg2+
-
 Ovis aries
6.3.1.2 Mg2+
-
 Bradyrhizobium japonicum
6.3.1.2 Mg2+
-
 Hordeum vulgare
6.3.1.2 Mg2+
-
 Spinacia oleracea
6.3.1.2 Mg2+
-
 Pisum sativum
6.3.1.2 Mg2+
-
 Zea mays
6.3.1.2 Mg2+
-
 Vigna radiata
6.3.1.2 Mg2+
-
 Oryza sativa
6.3.1.2 Mg2+
-
 Sorghum sp.
6.3.1.2 Mg2+
-
 Chlorella sp.
6.3.1.2 Mg2+
-
 Columba sp.
6.3.1.2 Mg2+
-
 Rattus norvegicus
6.3.1.2 Mg2+
-
 Senna obtusifolia
6.3.1.2 Mg2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 Mg2+
-
 Synechocystis sp.
6.3.1.2 Mg2+
-
 Homo sapiens
6.3.1.2 Mg2+
-
 Mus musculus
6.3.1.2 Mg2+
-
 Bacillus subtilis
6.3.1.2 Mg2+
-
 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.1.2 ATP + L-glutamate + NH3 Beta vulgaris
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Escherichia coli
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Triticum aestivum
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Ovis aries
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Bradyrhizobium japonicum
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Hordeum vulgare
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Spinacia oleracea
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Pisum sativum
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Zea mays
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Vigna radiata
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Oryza sativa
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Sorghum sp.
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Chlorella sp.
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Columba sp.
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Rattus norvegicus
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Senna obtusifolia
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Synechocystis sp.
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Homo sapiens
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Mus musculus
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Bacillus subtilis
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Mycobacterium tuberculosis
-
 ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 Mycobacterium tuberculosis H37Rv
-
 ADP + phosphate + L-glutamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.1.2 Bacillus subtilis P12425
-
-
6.3.1.2 Beta vulgaris
-
 isozyme GS2
-
6.3.1.2 Bradyrhizobium japonicum
-
 isozyme GS2
-
6.3.1.2 Chlorella sp.
-
-
-
6.3.1.2 Columba sp.
-
-
-
6.3.1.2 Escherichia coli
-
-
-
6.3.1.2 Homo sapiens P15104
-
-
6.3.1.2 Hordeum vulgare
-
 isozyme GS1
-
6.3.1.2 Hordeum vulgare P13564 isozyme GS2
-
6.3.1.2 Mus musculus P15105
-
-
6.3.1.2 Mycobacterium tuberculosis P9WN39
-
-
6.3.1.2 Mycobacterium tuberculosis H37Rv P9WN39
-
-
6.3.1.2 Oryza sativa
-
-
-
6.3.1.2 Ovis aries
-
-
-
6.3.1.2 Pisum sativum
-
-
-
6.3.1.2 Rattus norvegicus P09606
-
-
6.3.1.2 Salmonella enterica subsp. enterica serovar Typhimurium P0A1P6
-
-
6.3.1.2 Senna obtusifolia
-
 isozyme GS2
-
6.3.1.2 Sorghum sp.
-
-
-
6.3.1.2 Spinacia oleracea
-
-
-
6.3.1.2 Synechocystis sp. P77961
-
-
6.3.1.2 Triticum aestivum
-
 isozyme GS2
-
6.3.1.2 Vigna radiata
-
-
-
6.3.1.2 Zea mays
-
 isozyme GS1
-
6.3.1.2 Zea mays
-
 isozyme GS2
-

Reaction

EC Number Reaction Comment Organism Reaction ID
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Beta vulgaris
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Triticum aestivum
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Ovis aries
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Bradyrhizobium japonicum
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Hordeum vulgare
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Spinacia oleracea
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Pisum sativum
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Zea mays
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Vigna radiata
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Oryza sativa
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Sorghum sp.
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Chlorella sp.
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Columba sp.
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Rattus norvegicus
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Senna obtusifolia
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Salmonella enterica subsp. enterica serovar Typhimurium
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Synechocystis sp.
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Homo sapiens
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Mus musculus
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Bacillus subtilis
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism Mycobacterium tuberculosis
a
6.3.1.2 ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine reaction mechanism and transition state analogue, overview Escherichia coli
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.1.2 brain
-
 Ovis aries
-
6.3.1.2 leaf
-
 Spinacia oleracea
-
6.3.1.2 leaf
-
 Pisum sativum
-
6.3.1.2 liver
-
 Columba sp.
-
6.3.1.2 liver
-
 Rattus norvegicus
-
6.3.1.2 seed
-
 Sorghum sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.1.2 ATP + L-glutamate + NH3
-
 Beta vulgaris ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Escherichia coli ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Triticum aestivum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Ovis aries ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Bradyrhizobium japonicum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Hordeum vulgare ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Spinacia oleracea ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Pisum sativum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Zea mays ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Vigna radiata ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Oryza sativa ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Sorghum sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Chlorella sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Columba sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Rattus norvegicus ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Senna obtusifolia ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Synechocystis sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Homo sapiens ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Mus musculus ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Bacillus subtilis ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Mycobacterium tuberculosis ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Hordeum vulgare ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Spinacia oleracea ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Pisum sativum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Rattus norvegicus ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Mycobacterium tuberculosis ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Beta vulgaris ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Escherichia coli ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Triticum aestivum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Ovis aries ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Bradyrhizobium japonicum ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Zea mays ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Vigna radiata ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Oryza sativa ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Sorghum sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Chlorella sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Columba sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Senna obtusifolia ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Synechocystis sp. ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Homo sapiens ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Mus musculus ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP Bacillus subtilis ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3
-
 Mycobacterium tuberculosis H37Rv ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 ATP + L-glutamate + NH3 a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP Mycobacterium tuberculosis H37Rv ADP + phosphate + L-glutamine
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Beta vulgaris ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Escherichia coli ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Triticum aestivum ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Ovis aries ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Bradyrhizobium japonicum ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Hordeum vulgare ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Spinacia oleracea ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Pisum sativum ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Zea mays ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Vigna radiata ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Oryza sativa ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Sorghum sp. ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Chlorella sp. ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Columba sp. ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Rattus norvegicus ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Senna obtusifolia ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Synechocystis sp. ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Homo sapiens ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Mus musculus ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Bacillus subtilis ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Mycobacterium tuberculosis ?
-
 ?
6.3.1.2 additional information structure-activity relationship, overview Mycobacterium tuberculosis H37Rv ?
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.1.2 decamer
-
 Beta vulgaris
6.3.1.2 decamer
-
 Triticum aestivum
6.3.1.2 decamer
-
 Ovis aries
6.3.1.2 decamer
-
 Bradyrhizobium japonicum
6.3.1.2 decamer
-
 Hordeum vulgare
6.3.1.2 decamer
-
 Spinacia oleracea
6.3.1.2 decamer
-
 Pisum sativum
6.3.1.2 decamer
-
 Zea mays
6.3.1.2 decamer
-
 Vigna radiata
6.3.1.2 decamer
-
 Sorghum sp.
6.3.1.2 decamer
-
 Chlorella sp.
6.3.1.2 decamer
-
 Columba sp.
6.3.1.2 decamer
-
 Rattus norvegicus
6.3.1.2 decamer
-
 Senna obtusifolia
6.3.1.2 decamer
-
 Homo sapiens
6.3.1.2 decamer
-
 Mus musculus
6.3.1.2 dodecamer
-
 Escherichia coli
6.3.1.2 dodecamer
-
 Oryza sativa
6.3.1.2 dodecamer
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 dodecamer
-
 Synechocystis sp.
6.3.1.2 dodecamer
-
 Bacillus subtilis
6.3.1.2 dodecamer
-
 Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
6.3.1.2 Glutamine synthetase
-
 Beta vulgaris
6.3.1.2 Glutamine synthetase
-
 Escherichia coli
6.3.1.2 Glutamine synthetase
-
 Triticum aestivum
6.3.1.2 Glutamine synthetase
-
 Ovis aries
6.3.1.2 Glutamine synthetase
-
 Bradyrhizobium japonicum
6.3.1.2 Glutamine synthetase
-
 Hordeum vulgare
6.3.1.2 Glutamine synthetase
-
 Spinacia oleracea
6.3.1.2 Glutamine synthetase
-
 Pisum sativum
6.3.1.2 Glutamine synthetase
-
 Zea mays
6.3.1.2 Glutamine synthetase
-
 Vigna radiata
6.3.1.2 Glutamine synthetase
-
 Oryza sativa
6.3.1.2 Glutamine synthetase
-
 Sorghum sp.
6.3.1.2 Glutamine synthetase
-
 Chlorella sp.
6.3.1.2 Glutamine synthetase
-
 Columba sp.
6.3.1.2 Glutamine synthetase
-
 Rattus norvegicus
6.3.1.2 Glutamine synthetase
-
 Senna obtusifolia
6.3.1.2 Glutamine synthetase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 Glutamine synthetase
-
 Synechocystis sp.
6.3.1.2 Glutamine synthetase
-
 Homo sapiens
6.3.1.2 Glutamine synthetase
-
 Mus musculus
6.3.1.2 Glutamine synthetase
-
 Bacillus subtilis
6.3.1.2 Glutamine synthetase
-
 Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.1.2 ATP
-
 Beta vulgaris
6.3.1.2 ATP
-
 Escherichia coli
6.3.1.2 ATP
-
 Triticum aestivum
6.3.1.2 ATP
-
 Ovis aries
6.3.1.2 ATP
-
 Bradyrhizobium japonicum
6.3.1.2 ATP
-
 Hordeum vulgare
6.3.1.2 ATP
-
 Spinacia oleracea
6.3.1.2 ATP
-
 Pisum sativum
6.3.1.2 ATP
-
 Zea mays
6.3.1.2 ATP
-
 Vigna radiata
6.3.1.2 ATP
-
 Oryza sativa
6.3.1.2 ATP
-
 Sorghum sp.
6.3.1.2 ATP
-
 Chlorella sp.
6.3.1.2 ATP
-
 Columba sp.
6.3.1.2 ATP
-
 Rattus norvegicus
6.3.1.2 ATP
-
 Senna obtusifolia
6.3.1.2 ATP
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 ATP
-
 Synechocystis sp.
6.3.1.2 ATP
-
 Homo sapiens
6.3.1.2 ATP
-
 Mus musculus
6.3.1.2 ATP
-
 Bacillus subtilis
6.3.1.2 ATP
-
 Mycobacterium tuberculosis

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
6.3.1.2 0.00000047
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclopentanecarboxylic acid
-
 Vigna radiata
6.3.1.2 0.0000008
-
 4-phosphonohomoserine
-
 Vigna radiata
6.3.1.2 0.000005
-
 3-amino-5-[hydroxy(methyl)phosphoryl]tetrahydrofuran-3-carboxylic acid
-
 Vigna radiata
6.3.1.2 0.00031
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Vigna radiata
6.3.1.2 0.00059
-
 (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 0.0011
-
 Phosphinothricin
-
 Escherichia coli
6.3.1.2 0.0016
-
 4-phosphonohomoserine
-
 Escherichia coli
6.3.1.2 0.0018
-
 (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.002
-
 methionine sulfoximine
-
 Escherichia coli
6.3.1.2 0.002
-
 Phosphinothricin isozyme GS1 Zea mays
6.3.1.2 0.0021
-
 (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 0.003
-
 Phosphinothricin
-
 Spinacia oleracea
6.3.1.2 0.0035
-
 Phosphinothricin isozyme GS1 Hordeum vulgare
6.3.1.2 0.0037
-
 (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 0.004
-
 Phosphinothricin isozyme GS1 Zea mays
6.3.1.2 0.0057
-
 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Escherichia coli
6.3.1.2 0.006
-
 Phosphinothricin isozyme GS2 Hordeum vulgare
6.3.1.2 0.0065
-
 Phosphinothricin isozyme GS2 Beta vulgaris
6.3.1.2 0.007
-
 (2S)-2-amino-4-(hydroxyamino)butanoic acid
-
 Ovis aries
6.3.1.2 0.0079
-
 (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.008
-
 Phosphinothricin
-
 Sorghum sp.
6.3.1.2 0.008
-
 Phosphinothricin isozyme GS2 Bradyrhizobium japonicum
6.3.1.2 0.0085
-
 (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.0085
-
 Phosphinothricin isozyme GS2 Senna obtusifolia
6.3.1.2 0.009
-
 Phosphinothricin isozyme GS2 Triticum aestivum
6.3.1.2 0.012
-
 4-phosphonohomoserine
-
 Spinacia oleracea
6.3.1.2 0.014
-
 4-phosphonohomoserine
-
 Sorghum sp.
6.3.1.2 0.016
-
 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Spinacia oleracea
6.3.1.2 0.0176
-
 (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.02
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Sorghum sp.
6.3.1.2 0.021
-
 (2S)-2-amino-4-(hydroxyamino)butanoic acid
-
 Bradyrhizobium japonicum
6.3.1.2 0.0216
-
 (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.022
-
 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Sorghum sp.
6.3.1.2 0.024
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Escherichia coli
6.3.1.2 0.024
-
 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Sorghum sp.
6.3.1.2 0.025
-
 4-phosphononorvaline
-
 Escherichia coli
6.3.1.2 0.0252
-
 Phosphinothricin
-
 Ovis aries
6.3.1.2 0.032
-
 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.033
-
 [[(3,5-dichlorophenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.033
-
 O-acetyl-4-phosphonohomoserine
-
 Escherichia coli
6.3.1.2 0.033
-
 D,L-phosphinothricin
-
 Oryza sativa
6.3.1.2 0.04
-
 5-oxolysine
-
 Salmonella enterica subsp. enterica serovar Typhimurium
6.3.1.2 0.0458
-
 (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.047
-
 4-phosphonohomoserine
-
 Ovis aries
6.3.1.2 0.05
-
 2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 0.051
-
 methionine sulfone amine
-
 Escherichia coli
6.3.1.2 0.054
-
 L-glutamyl gamma-phosphinic acid
-
 Escherichia coli
6.3.1.2 0.056
-
 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Rattus norvegicus
6.3.1.2 0.064
-
 [[(pyridin-2-ylmethyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.067
-
 4-phosphononorvaline
-
 Sorghum sp.
6.3.1.2 0.069
-
 [[(5-chloropyridin-2-yl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.072
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Spinacia oleracea
6.3.1.2 0.073
-
 Phosphinothricin
-
 Pisum sativum
6.3.1.2 0.075
-
 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Escherichia coli
6.3.1.2 0.1
-
 methionine sulfoximine
-
 Spinacia oleracea
6.3.1.2 0.111
-
 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Ovis aries
6.3.1.2 0.125
-
 (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid
-
 Ovis aries
6.3.1.2 0.125
-
 4-[hydroxy(methyl)phosphoryl]isovaline
-
 Ovis aries
6.3.1.2 0.133
-
 (2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.14
-
 4-phosphononorvaline
-
 Vigna radiata
6.3.1.2 0.161
-
 methionine sulfoximine
-
 Pisum sativum
6.3.1.2 0.17
-
 [[(4-methylphenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.178
-
 O-acetyl-4-phosphonohomoserine
-
 Sorghum sp.
6.3.1.2 0.21
-
 methionine sulfoximine
-
 Ovis aries
6.3.1.2 0.243
-
 [(pyridin-2-ylamino)methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.25
-
 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 0.31
-
 3-[(phosphonoacetyl)amino]alanine
-
 Pisum sativum
6.3.1.2 0.32
-
 Phosphinothricin
-
 Rattus norvegicus
6.3.1.2 0.32
-
 (2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid
-
 Spinacia oleracea
6.3.1.2 0.334
-
 2-[(diphosphonomethyl)amino]pyridine-3-carboxylic acid
-
 Oryza sativa
6.3.1.2 0.347
-
 4-phosphononorvaline
-
 Ovis aries
6.3.1.2 0.49
-
 5-oxolysine
-
 Zea mays
6.3.1.2 0.492
-
 4-phosphononorvaline
-
 Spinacia oleracea
6.3.1.2 0.59
-
 5-oxo-6-phosphononorleucine
-
 Pisum sativum
6.3.1.2 0.62
-
 4-fluoroglutamic acid
-
 Chlorella sp.
6.3.1.2 0.66
-
 5-oxo-6-phosphononorleucine
-
 Ovis aries
6.3.1.2 0.738
-
 [[(3-nitrophenyl)amino]methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 0.75
-
 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid
-
 Ovis aries
6.3.1.2 0.79
-
 4-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
-
 Rattus norvegicus
6.3.1.2 0.85
-
 5-oxolysine
-
 Zea mays
6.3.1.2 0.91
-
 3-[(phosphonoacetyl)amino]alanine
-
 Escherichia coli
6.3.1.2 1
-
 (2S)-2-amino-4-[(3S)-3-hydroxy-2-oxoazetidin-3-yl]butanoic acid
-
 Pisum sativum
6.3.1.2 1.1
-
 [(cyclohexylamino)methanediyl]bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 1.2
-
 (2R,3S)-3-aminooxetane-2-carboxylic acid
-
 Bacillus subtilis
6.3.1.2 1.2
-
 [1-amino-3-(S-methylsulfonimidoyl)propyl]phosphonic acid
-
 Escherichia coli
6.3.1.2 1.3
-
 (2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid
-
 Mus musculus
6.3.1.2 1.3
-
 4-amino-4-phosphonobutanoic acid
-
 Rattus norvegicus
6.3.1.2 1.4
-
 2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid
-
 Ovis aries
6.3.1.2 1.42
-
 2-amino-4-hydroxyglutaric acid
-
 Chlorella sp.
6.3.1.2 1.8
-
 3-[(diphosphonomethyl)amino]benzoic acid
-
 Oryza sativa
6.3.1.2 2.1
-
 (1-amino-4-methoxy-4-oxobutyl)phosphonic acid
-
 Rattus norvegicus
6.3.1.2 2.2
-
 2-amino-4-[methyl(phosphonomethyl)phosphoryl]butanoic acid
-
 Pisum sativum
6.3.1.2 3
-
 L-glutamyl gamma-phosphinic acid
-
 Columba sp.
6.3.1.2 3.4
-
 (2R,3S)-3-aminooxetane-2-carboxylic acid plastidic isozyme Spinacia oleracea
6.3.1.2 4
-
 (2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid
-
 Mus musculus
6.3.1.2 4.47
-
 ([[2-(4-hydroxyphenyl)ethyl]amino]methanediyl)bis(phosphonic acid)
-
 Oryza sativa
6.3.1.2 4.8
-
 5-oxo-6-phosphononorleucine
-
 Escherichia coli
6.3.1.2 5
-
 methionine sulfoxide above Escherichia coli
6.3.1.2 5.5
-
 (1,4-diamino-4-oxobutyl)phosphonic acid
-
 Rattus norvegicus
6.3.1.2 6.2
-
 (3,4-diamino-4-oxobutyl)methylphosphinic acid
-
 Rattus norvegicus
6.3.1.2 6.3
-
 4-phosphonoisovaline
-
 Rattus norvegicus
6.3.1.2 8.7
-
 (3-amino-4-methoxy-4-oxobutyl)methylphosphinic acid
-
 Rattus norvegicus
6.3.1.2 9.5
-
 4-amino-4-[hydroxy(methyl)phosphoryl]pentanoic acid
-
 Rattus norvegicus
6.3.1.2 16
-
 4-amino-4-phosphonopentanoic acid
-
 Rattus norvegicus