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Literature summary extracted from

  • Toyomasu, T.; Tsukahara, M.; Kaneko, A.; Niida, R.; Mitsuhashi, W.; Dairi, T.; Kato, N.; Sassa, T.
    Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi (2007), Proc. Natl. Acad. Sci. USA, 104, 3084-3088.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.43 heterologous expression of PaFS alone results in the accumulation of fusicocca-2,10 (14)-diene in Escherichia coli cells Diaporthe amygdali

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.43 geranylgeranyl diphosphate Diaporthe amygdali the enzyme contains two domains, an N-terminal terpene cyclase domain and a C-terminal prenyltransferase domain, and converts isoprene units sequentially into geranylgeranyl diphosphate and then into fusicocca-2,10 (14)-diene fusicocca-2,10(14)-diene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.43 Diaporthe amygdali A2PZA5
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.43 mycelium
-
 Diaporthe amygdali
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.43 geranylgeranyl diphosphate
-
 Diaporthe amygdali fusicocca-2,10(14)-diene + diphosphate
-
 ?
4.2.3.43 geranylgeranyl diphosphate the enzyme contains two domains, an N-terminal terpene cyclase domain and a C-terminal prenyltransferase domain, and converts isoprene units sequentially into geranylgeranyl diphosphate and then into fusicocca-2,10 (14)-diene Diaporthe amygdali fusicocca-2,10(14)-diene + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.43 fusicoccadiene synthase
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 Diaporthe amygdali
4.2.3.43 PaFS
-
 Diaporthe amygdali