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Literature summary extracted from

  • Yang, E.S.; Park, J.W.
    Regulation of ethanol-induced toxicity by mitochondrial NADP+-dependent isocitrate dehydrogenase (2009), Biochimie, 91, 1020-1028.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.42 expressed in Hep-G2 cells Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.42 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.42 additional information Mus musculus IDPm expression in HepG2 cells regulates ethanol-induced toxicity ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.42 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.42 isocitrate + NADP+
-
 Mus musculus 2-oxoglutarate + CO2 + NADPH + H+
-
 ?
1.1.1.42 additional information IDPm expression in HepG2 cells regulates ethanol-induced toxicity Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.42 ICDH
-
 Mus musculus
1.1.1.42 IDPm
-
 Mus musculus
1.1.1.42 mitochondrial NADP+-dependent isocitrate dehydrogenase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.42 NADP+
-
 Mus musculus