Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Baba, S.P.; Wetzelberger, K.; Hoetker, J.D.; Bhatnagar, A.
    Posttranslational glutathiolation of aldose reductase (AKR1B1): a possible mechanism of protein recovery from S-nitrosylation (2009), Chem. Biol. Interact., 178, 250-258.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.21 sorbinil
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.21 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.1.1.21 glutathionylation the activity of AKR1B1 is regulated by nitric oxide and the de-nitrosylation of AKR1B1 is mediated or facilitated by intracellular reductants such as glutathione and ascorbate Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.21 DL-glyceraldehyde + NADPH + H+
-
Homo sapiens glycerol + NADP+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.21 AKR1B1
-
Homo sapiens
1.1.1.21 aldose reductase
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.21 NADPH
-
Homo sapiens