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Literature summary extracted from
- The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy (2009), J. Cell Biol., 185, 1181-1194.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.99.29 | endoplasmic reticulum | - |
Drosophila melanogaster | 5783 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.99.29 | Iron | - |
Drosophila melanogaster |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.99.29 | 39000 | - |
determined by SDS-PAGE and Western Blot analysis | Drosophila melanogaster |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.99.29 | additional information | Drosophila melanogaster | DOHH hydroxylates deoxyhypusine and irreversibly completes the hypusination process, the eukaryotic translation initiation factor eIF-5A is the sole known target of hypusination | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.99.29 | Drosophila melanogaster | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.99.29 | garland cell | larval garland cell | Drosophila melanogaster | - |
| 1.14.99.29 | larva | - |
Drosophila melanogaster | - |
| 1.14.99.29 | wing disc | larval imaginal disc cell | Drosophila melanogaster | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.99.29 | additional information | DOHH hydroxylates deoxyhypusine and irreversibly completes the hypusination process, the eukaryotic translation initiation factor eIF-5A is the sole known target of hypusination | Drosophila melanogaster | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.99.29 | deoxyhypusine hydroxylase | - |
Drosophila melanogaster |
| 1.14.99.29 | deoxyhypusine hydroxylase homologue nero | - |
Drosophila melanogaster |
| 1.14.99.29 | DOOH | - |
Drosophila melanogaster |
| 1.14.99.29 | nero | - |
Drosophila melanogaster |
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Release 2023.1 (January 2023)
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