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Literature summary extracted from
- Molecular cloning and sequence analysis of (S)-N-methylcoclaurine-3'-hydroxylase gene in Coptis chinensis (2008), Zhong Cao Yao, 39, 419-423.
No PubMed abstract available
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.14.14.102 | medicine | traditional Chinese medicinal plant containing benzylisoquinoline alkaloids as active agents | Coptis chinensis |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.14.102 | PDR-amplification | Coptis chinensis |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.14.102 | 55040 | - |
calculated from amino acids, 488 amino acids, 1680 bp | Coptis chinensis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 | Coptis chinensis | - |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.102 | Coptis chinensis | B2BF50 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.102 | leaf | - |
Coptis chinensis | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Coptis chinensis | (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.102 | (S)-N-methylcoclaurine-3'-hydroxylase | - |
Coptis chinensis |
| 1.14.14.102 | CYP80B3 | - |
Coptis chinensis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.102 | heme | - |
Coptis chinensis | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.14.14.102 | metabolism | benzylisoquinoline alkaloid biosynthesis | Coptis chinensis |
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Release 2023.1 (January 2023)
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