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Literature summary extracted from
- Isolation of herbicide-resistant 4-hydroxyphenylpyruvate dioxygenase from cultured Coptis japonica cells (2008), Biosci. Biotechnol. Biochem., 72, 3059-3062.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.13.11.27 | expression in Escherichia coli | Coptis japonica var. dissecta |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.11.27 | 4-(2,4-dichlorobenzyl)-1,3-dimethyl-5-hydroxypyrazole | - |
Coptis japonica var. dissecta |  |
| 1.13.11.27 | benzobicyclon hydrolysate | - |
Coptis japonica var. dissecta | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.13.11.27 | 0.0432 | - |
4-hydroxyphenylpyruvate | - |
Coptis japonica var. dissecta | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.11.27 | Fe2+ | - |
Coptis japonica var. dissecta | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | Coptis japonica var. dissecta | - |
homogentisate + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.11.27 | Coptis japonica var. dissecta | A7BG64 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | - |
Coptis japonica var. dissecta | homogentisate + CO2 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.13.11.27 | 4-hydroxyphenylpyruvare dioxygenase | - |
Coptis japonica var. dissecta |
| 1.13.11.27 | HPPD | - |
Coptis japonica var. dissecta |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.13.11.27 | 0.00234 | - |
recombinant enzyme | Coptis japonica var. dissecta | benzobicyclon hydrolysate | |
| 1.13.11.27 | 0.00675 | - |
recombinant enzyme | Coptis japonica var. dissecta | 4-(2,4-dichlorobenzyl)-1,3-dimethyl-5-hydroxypyrazole | |
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Release 2023.1 (January 2023)
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