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Literature summary extracted from

  • Wu, X.; Hua, X.
    Menin, histone H3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective (2008), Curr. Mol. Med., 8, 805-815.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.354 Drosophila melanogaster
-
-
-
2.1.1.354 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.354 S-adenosyl-L-methionine + histone H3(K4) menin appears to be essential for MLL-mediated histone H3(K4) methylation Drosophila melanogaster ?
-
 ?
2.1.1.354 S-adenosyl-L-methionine + histone H3(K79)
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.354 DOT1L
-
 Homo sapiens
2.1.1.354 histone H3 methyltransferase
-
 Drosophila melanogaster
2.1.1.354 histone H3 methyltransferase
-
 Homo sapiens
2.1.1.354 mixed lineage leukemia protein
-
 Drosophila melanogaster
2.1.1.354 MLL
-
 Drosophila melanogaster