EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.1.1.355 | nucleus | - |
Drosophila melanogaster | 5634 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.355 | Drosophila melanogaster | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.1.355 | adult | - |
Drosophila melanogaster | - |
2.1.1.355 | head | - |
Drosophila melanogaster | - |
2.1.1.355 | larva | - |
Drosophila melanogaster | - |
2.1.1.355 | pupa | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.355 | S-adenosyl-L-methionine + histone H3(K9) | - |
Drosophila melanogaster | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.355 | G9a | - |
Drosophila melanogaster |
2.1.1.355 | H3K9 methyltransferase | - |
Drosophila melanogaster |
2.1.1.355 | H3K9-specific SET domain methyltransferase | - |
Drosophila melanogaster |
2.1.1.355 | SETDB1 | - |
Drosophila melanogaster |
2.1.1.355 | SU(VAR)3-9 | - |
Drosophila melanogaster |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.1.1.355 | malfunction | knockdown of G9a or SETDB1 throughout development with an ACT5C-GAL4 driver produces organism- level defects only in the case of dSETDB1 | Drosophila melanogaster |
2.1.1.355 | physiological function | SETDB1 acts to maintain heterochromatin during metamorphosis, at a later stage in development than the reported action of SU(VAR)3-9, depletion of both of these enzymes has less deleterious effect than depletion of one, SETDB1 acts as a heterochromatin maintenance factor that may be required for the persistence of earlier developmental events normally governed by SU(VAR)3-9 | Drosophila melanogaster |