Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chien, S.C.; Yang, C.W.; Tseng, Y.H.; Tsay, H.S.; Kuo, Y.H.; Wang, S.Y.
    Lonicera hypoglauca inhibits xanthine oxidase and reduces serum uric acid in mice (2009), Planta Med., 75, 302-306.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 allopurinol
-
 Mus musculus
1.17.3.2 ioniceraflavone i.e. 5,5'',7,7''-tetrahydroxy-2,2''-di(p-hydroxyphenyl)-2'',3''-dihydro[3,6'']bichromenyl-4,4''-dione, from ethanolic leaf extracts of Lonicera hypoglauca Mus musculus
1.17.3.2 additional information ethanol leaf extracts of Lonicera hypoglauca, an endemic rattan growing in Taiwan, inhibits xanthine oxidase and reduces serum uric acid in mice, overview Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + O2 + H2O Mus musculus
-
 urate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + O2 + H2O
-
 Mus musculus urate + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.17.3.2 XOD
-
 Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.3.2 7.5
-
 assay at Mus musculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.17.3.2 additional information
-
 IC50 of licewraflavone is 0.00085 mg/ml and for allopurinol is 0.00040 mg/ml Mus musculus additional information

General Information

EC Number General Information Comment Organism
1.17.3.2 malfunction the enzyme is a key enzyme in th epathogenesis of hyperuricemia Mus musculus