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Literature summary extracted from
- FMN is covalently attached to a threonine residue in the NqrB and NqrC subunits of Na+-translocating NADH-quinone reductase from Vibrio alginolyticus (2001), FEBS Lett., 488, 5-8.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.2.1.1 | membrane | - |
Vibrio alginolyticus | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.1.1 | Na+ | the reaction catalyzed by subunits NqrA to NqrE to produce ubiquinol specifically requires Na+ for activity. The reaction catalyzed by subunit NqrF which reduces ubiquinone by a one-electron transfer pathway to produce ubisemiquinone radical does not require Na+ for activity | Vibrio alginolyticus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.1.1 | NADH + H+ + ubiquinone + n Na+/in | Vibrio alginolyticus | - |
NAD+ + ubiquinol + n Na+/out | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.2.1.1 | Vibrio alginolyticus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.1.1 | NADH + H+ + ubiquinone + n Na+/in | - |
Vibrio alginolyticus | NAD+ + ubiquinol + n Na+/out | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.2.1.1 | heterohexamer | - |
Vibrio alginolyticus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.2.1.1 | Na+-translocating NADH-quinone oxidoreductase | - |
Vibrio alginolyticus |
| 7.2.1.1 | NQR | - |
Vibrio alginolyticus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.1.1 | FAD | subunit NqrF contains non-covalently bound FAD | Vibrio alginolyticus | |
| 7.2.1.1 | FMN | part of NqrB and NqrC subunits | Vibrio alginolyticus | |
| 7.2.1.1 | NADH | - |
Vibrio alginolyticus | |
| 7.2.1.1 | riboflavin | - |
Vibrio alginolyticus | |
| 7.2.1.1 | [2Fe-2S]-center | - |
Vibrio alginolyticus | |
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Release 2023.1 (January 2023)
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