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Literature summary extracted from

  • Mojzita, D.; Vuoristo, K.; Koivistoinen, O.M.; Penttilae, M.; Richard, P.
    The true L-xylulose reductase of filamentous fungi identified in Aspergillus niger (2010), FEBS Lett., 584, 3540-3544.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.10 expression in Saccharomyces cerevisiae Aspergillus niger

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.10 25
-
 L-xylulose pH 7.0, 22°C Aspergillus niger

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.10 Aspergillus niger
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.10 1
-
 substrate xylitol, pH 7.0, 22°C Aspergillus niger
1.1.1.10 1.4
-
 substrate ribulose, pH 7.0, 22°C Aspergillus niger
1.1.1.10 1.8
-
 substrate L-xylulose, pH 7.0, 22°C Aspergillus niger

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.10 D-ribulose + NADPH + H+
-
 Aspergillus niger D-ribitol + NADP+
-
 ?
1.1.1.10 L-xylulose + NADPH + H+
-
 Aspergillus niger L-xylitol + NADP+
-
 r
1.1.1.10 additional information no substrate: D-fructose, D-sorbose, L-sorbose, xylitol, D-arabitol, L-arabitol, ribitol, D-sorbitol and galactitol Aspergillus niger ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.10 additional information no activitiy with NADH Aspergillus niger
1.1.1.10 NADPH
-
 Aspergillus niger

Expression

EC Number Organism Comment Expression
1.1.1.10 Aspergillus niger expression is upregulated upon growth on L-arabinose up

General Information

EC Number General Information Comment Organism
1.1.1.10 physiological function deletion results in a strain lacking the NADPH-specific L-xylulose reductase activity and having reduced growth on L-arabinose Aspergillus niger