Literature summary extracted from
Sauvage, E.; Zervosen, A.; Dive, G.; Herman, R.; Amoroso, A.; Joris, B.; Fonze, E.; Pratt, R.F.; Luxen, A.; Charlier, P.; Kerff, F.
Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate (2009), J. Am. Chem. Soc., 131, 15262-15269.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
3.5.2.6 |
hanging drop vapor diffusion, crystals are soaked with a solution of 6-beta-iodopenicillanic acid and the structure solved at 1.65 A |
Bacillus subtilis |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
3.5.2.6 |
6-beta-iodopenicillanic acid |
the nature of the interactions of the rearranged inhibitor with conserved active site residues, the position of the inhibitor carboxylate and its interactions with Asn132, Asn104, and Asn170 |
Bacillus subtilis |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
3.5.2.6 |
Bacillus subtilis |
- |
BS3 |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
3.5.2.6 |
- |
Bacillus subtilis |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
3.5.2.6 |
class A beta-lactamase |
- |
Bacillus subtilis |