EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.4.3.2 | 4,5-dehydro-(S)-lysine | suicide inactivator | Clostridium subterminale |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
5.4.3.2 | Fe2+ | the activity is modestly increased by the addition of ferrous iron | Clostridium subterminale |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.4.3.2 | Clostridium subterminale | - |
- |
- |
5.4.3.2 | Clostridium subterminale SB4 | - |
- |
- |
5.4.3.3 | Acetoanaerobium sticklandii | - |
- |
- |
5.4.3.3 | Porphyromonas gingivalis | - |
- |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
5.4.3.2 | the enzyme is extremely sensitive to oxidation by air and is active under anaerobic conditions | Clostridium subterminale |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.3.2 | (S)-lysine | - |
Clostridium subterminale | (S)-beta-lysine | - |
r | |
5.4.3.2 | (S)-lysine | - |
Clostridium subterminale SB4 | (S)-beta-lysine | - |
r | |
5.4.3.3 | (R)-lysine | best substrate | Porphyromonas gingivalis | ? | - |
? | |
5.4.3.3 | (S)-beta-lysine | - |
Acetoanaerobium sticklandii | 3,5-diaminohexanoate | - |
r | |
5.4.3.3 | (S)-beta-lysine | - |
Porphyromonas gingivalis | 3,5-diaminohexanoate | - |
r | |
5.4.3.3 | (S)-lysine | - |
Porphyromonas gingivalis | ? | - |
? | |
5.4.3.3 | 4-thia-(R)-lysine | 4-thia-(R)-lysine reacts with the complex of pyridoxal 5'-phosphate, adenosylcobalamin, and lysine 5,6-aminomutase to generate cob(II)alamin, 5'-deoxyadenosine, and 4-thialysine-based free radicals | Acetoanaerobium sticklandii | ? | - |
? | |
5.4.3.3 | 4-thia-(S)-lysine | 4-thia-(S)-lysine reacts with the complex of pyridoxal 5'-phosphate, adenosylcobalamin, and lysine 5,6-aminomutase to generate cob(II)alamin, 5'-deoxyadenosine, and 4-thialysine-based free radicals | Acetoanaerobium sticklandii | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
5.4.3.3 | heterodimer | - |
Acetoanaerobium sticklandii |
5.4.3.3 | heterodimer | - |
Porphyromonas gingivalis |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.4.3.2 | LAM | - |
Clostridium subterminale |
5.4.3.3 | (R)-lysine mutase | formerly | Acetoanaerobium sticklandii |
5.4.3.3 | (R)-lysine mutase | formerly | Porphyromonas gingivalis |
5.4.3.3 | beta-Lysine mutase | - |
Acetoanaerobium sticklandii |
5.4.3.3 | beta-Lysine mutase | - |
Porphyromonas gingivalis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
5.4.3.2 | 4Fe-4S-center | - |
Clostridium subterminale | |
5.4.3.2 | pyridoxal 5'-phosphate | dependent on | Clostridium subterminale | |
5.4.3.3 | adenosylcobalamin | - |
Acetoanaerobium sticklandii | |
5.4.3.3 | adenosylcobalamin | - |
Porphyromonas gingivalis | |
5.4.3.3 | pyridoxal 5'-phosphate | - |
Acetoanaerobium sticklandii | |
5.4.3.3 | pyridoxal 5'-phosphate | - |
Porphyromonas gingivalis |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.4.3.3 | 0.00043 | - |
(S)-lysine | pH and temperature not specified in the publication | Porphyromonas gingivalis | |
5.4.3.3 | 0.48 | - |
(S)-beta-lysine | pH and temperature not specified in the publication | Porphyromonas gingivalis | |
5.4.3.3 | 0.63 | - |
(R)-lysine | pH and temperature not specified in the publication | Porphyromonas gingivalis |