Any feedback?
Literature summary extracted from
- Host expression of methylmalonyl-CoA mutase and tuberculosis: a missing link? (2011), Med. Hypotheses, 76, 361-364.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.2 | Sus scrofa | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.2 | (R)-2-methylmalonyl-CoA | - |
Sus scrofa | succinyl-CoA | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.99.2 | MCM | - |
Sus scrofa |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.99.2 | adenosylcobalamin | - |
Sus scrofa | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 5.4.99.2 | physiological function | methylmalonyl-CoA mutase (MUT) expression influences the risk of acquiring Mycobacterium bovis infection and developing bovine tuberculosis. Genetically-defined higher host MUT expression levels result in lower serum cholesterol concentration and tissue deposits that increase the protective immune response to Mycobacterium bovis, thus resulting in resistance to bovine tuberculosis and better response to Mycobacterium bovis bacilli Calmette-Guerin vaccination | Sus scrofa |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
