EC Number | Application | Comment | Organism |
---|---|---|---|
4.1.1.90 | medicine | single nucleotide polymorphism in the GGCX gene may affect the dose of warfarin and other vitamin K antagonists | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.1.1.90 | additional information | GGCX single nucleotide polymorphism rs11676382(but not rs12714145) is a significant predictor of residual warfarin dosing error and is associated with a 6.1% reduction in warfarin dose per G allele | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.1.1.90 | endoplasmic reticulum membrane | - |
Homo sapiens | 5789 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.90 | L-glutamate + CO2 + O2 + vitamin K hydroquinone | Homo sapiens | - |
gamma-carboxy L-glutamate + vitamin K epoxide + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.90 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.90 | L-glutamate + CO2 + O2 + vitamin K hydroquinone | - |
Homo sapiens | gamma-carboxy L-glutamate + vitamin K epoxide + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.1.1.90 | gamma-glutamyl carboxylase | - |
Homo sapiens |
4.1.1.90 | GGCX | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.90 | vitamin K | - |
Homo sapiens |