Literature summary extracted from

Fiala, K.A.; Suo, Z.
Mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase IV (2004), Biochemistry, 43, 2116-2125.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.7	Saccharolobus solfataricus	Q97W02	-	-
2.7.7.7	Saccharolobus solfataricus P2	Q97W02	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.7	DNA 21/41-mer + dTTP	kinetic mechanism for DNA polymerization is proposed, the enzyme utilizes an induced-fit mechanism to select correct incoming nucleotides	Saccharolobus solfataricus	? + diphosphate	-	?
2.7.7.7	DNA 21/41-mer + dTTP	kinetic mechanism for DNA polymerization is proposed, the enzyme utilizes an induced-fit mechanism to select correct incoming nucleotides	Saccharolobus solfataricus P2	? + diphosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.7.7	DNA polymerase IV	-	Saccharolobus solfataricus
2.7.7.7	Dpo4	-	Saccharolobus solfataricus

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
2.7.7.7	37	-	assay at	Saccharolobus solfataricus

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.7.7.7	7.5	-	assay at	Saccharolobus solfataricus

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Release 2023.1 (January 2023)