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Literature summary extracted from

  • Beattie, T.R.; Bell, S.D.
    Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation (2012), EMBO J., 31, 1556-1567.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.1.99.B1 Saccharolobus solfataricus Q980U8
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.99.B1 additional information reconstitution of Okazaki fragment maturation in vitro using proteins derived from the archaeon Sulfolobus solfataricus: six proteins are necessary and sufficient for coupled DNA synthesis, RNA primer removal and DNA ligation. PolB1, Fen1 and Lig1 provide the required catalytic activities, with coordination of their activities dependent upon the DNA sliding clamp, proliferating cell nuclear antigen Saccharolobus solfataricus ?
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