EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.5.3.21 | 2.5 | - |
4-methylaminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans | |
1.5.3.21 | 6.66 | - |
4-aminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.5.3.21 | 46000 | - |
x * 46100, calculated, x * 46000, SDS-PAGE | Paenarthrobacter nicotinovorans |
1.5.3.21 | 46100 | - |
x * 46100, calculated, x * 46000, SDS-PAGE | Paenarthrobacter nicotinovorans |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.5.3.19 | Paenarthrobacter nicotinovorans | - |
- |
- |
1.5.3.21 | Paenarthrobacter nicotinovorans | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.5.3.21 | 4-aminobutanoate + O2 + H2O | - |
Paenarthrobacter nicotinovorans | succinate semialdehyde + NH3 + H2O2 | - |
? | |
1.5.3.21 | 4-methylaminobutanoate + O2 + H2O | - |
Paenarthrobacter nicotinovorans | succinate semialdehyde + methylamine + H2O2 | - |
? | |
1.5.3.21 | additional information | no substrates: spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyric acid, methylaminopropionnitrile, methylaminopropylamine | Paenarthrobacter nicotinovorans | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.5.3.21 | ? | x * 46100, calculated, x * 46000, SDS-PAGE | Paenarthrobacter nicotinovorans |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.5.3.21 | MAO | - |
Paenarthrobacter nicotinovorans |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.5.3.21 | 22 | - |
assay at | Paenarthrobacter nicotinovorans |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.5.3.21 | 878 | - |
4-aminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans | |
1.5.3.21 | 1230 | - |
4-methylaminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.5.3.21 | 9.8 | - |
- |
Paenarthrobacter nicotinovorans |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.5.3.21 | FAD | noncovalently bound | Paenarthrobacter nicotinovorans |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.5.3.19 | physiological function | in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 1.5.3.19. In an alternative pathway, amine oxidase, EC 1.5.3.21, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate | Paenarthrobacter nicotinovorans |
1.5.3.21 | physiological function | in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 1.5.3.19. In an alternative pathway, amine oxidase, EC 1.5.3.21, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate | Paenarthrobacter nicotinovorans |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.5.3.21 | 131 | - |
4-aminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans | |
1.5.3.21 | 490 | - |
4-methylaminobutanoate | pH 9.8, 22°C | Paenarthrobacter nicotinovorans |