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Literature summary extracted from

  • Luzardo, R.; Silva, P.A.; Einicker-Lamas, M.; Ortiz-Costa, S.; do Carmo, M.d.a..G.; Vieira-Filho, L.D.; Paixao, A.D.; Lara, L.S.; Vieyra, A.
    Metabolic programming during lactation stimulates renal Na+ transport in the adult offspring due to an early impact on local angiotensin II pathways (2011), PLoS ONE, 6, e21232.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.3 angiotensin II physiological activation at femtomolar concentration. The activation by angiotensin II is completely abolished in the adult progeny of rats that are undernourished during lactation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.3 Furosemide
-
 Rattus norvegicus
7.2.2.3 additional information not inhibited by ouabain Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.3 membrane
-
 Rattus norvegicus 16020
-

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.3 renal proximal tubule
-
 Rattus norvegicus
-

Synonyms

EC Number Synonyms Comment Organism
7.2.2.3 Na+-ATPase
-
 Rattus norvegicus

Expression

EC Number Organism Comment Expression
7.2.2.3 Rattus norvegicus Na+-ATPase activity increases more than 2fold in the adult progeny of rats that are undernourished during lactation. Its physiological activation by angiotensin II is completely abolished up