Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Runquist, D.; Hahn-Haegerdal, B.; Bettiga, M.
    Increased ethanol productivity in xylose-utilizing Saccharomyces cerevisiae via a randomly mutagenized xylose reductase (2010), Appl. Environ. Microbiol., 76, 7796-7802.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.307 gene XYL1 Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.307 N272D site-directed mutagenesis, results in strain TMB 3422, the mutation enables the yeast for anaerobic growth on xylose displayed higher aerobic growth rates Saccharomyces cerevisiae
1.1.1.307 N272D/P275Q site-directed mutagenesis, results in strain TMB 3421, the mutations enable the yeast for anaerobic growth on xylose displayed higher aerobic growth rates Saccharomyces cerevisiae
1.1.1.307 P275Q site-directed mutagenesis, results in strain TMB 3423, the mutation enables the yeast for anaerobic growth on xylose displayed higher aerobic growth rates Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.307 xylitol + NAD+ Saccharomyces cerevisiae
-
D-xylose + NADH + H+
-
r
1.1.1.307 xylitol + NAD+ Saccharomyces cerevisiae TMB 3420
-
D-xylose + NADH + H+
-
r
1.1.1.307 xylitol + NADP+ Saccharomyces cerevisiae
-
D-xylose + NADPH + H+
-
r
1.1.1.307 xylitol + NADP+ Saccharomyces cerevisiae TMB 3420
-
D-xylose + NADPH + H+
-
r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.307 Saccharomyces cerevisiae
-
-
-
1.1.1.307 Saccharomyces cerevisiae TMB 3420
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.307 xylitol + NAD+
-
Saccharomyces cerevisiae D-xylose + NADH + H+
-
r
1.1.1.307 xylitol + NAD+
-
Saccharomyces cerevisiae TMB 3420 D-xylose + NADH + H+
-
r
1.1.1.307 xylitol + NADP+
-
Saccharomyces cerevisiae D-xylose + NADPH + H+
-
r
1.1.1.307 xylitol + NADP+
-
Saccharomyces cerevisiae TMB 3420 D-xylose + NADPH + H+
-
r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.307 NAD+
-
Saccharomyces cerevisiae
1.1.1.307 NADH
-
Saccharomyces cerevisiae
1.1.1.307 NADP+
-
Saccharomyces cerevisiae
1.1.1.307 NADPH
-
Saccharomyces cerevisiae