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Literature summary extracted from

  • McLean, K.J.; Cheesman, M.R.; Rivers, S.L.; Richmond, A.; Leys, D.; Chapman, S.K.; Reid, G.A.; Price, N.C.; Kelly, S.M.; Clarkson, J.; Smith, W.E.; Munro, A.W.
    Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis (2002), J. Inorg. Biochem., 91, 527-541.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.70 expressed in Escherichia coli HMS174 (DE3) cells Mycobacterium tuberculosis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.19.70 clotrimazole
-
 Mycobacterium tuberculosis
1.14.19.70 econazole
-
 Mycobacterium tuberculosis
1.14.19.70 miconazole
-
 Mycobacterium tuberculosis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.19.70 43126
-
 x * 43126, calculated from amino acid sequence Mycobacterium tuberculosis
1.14.19.70 43128
-
 x * 43128, electrospray ionization mass spectrometry Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.70 Mycobacterium tuberculosis P9WPP7
-
-
1.14.19.70 Mycobacterium tuberculosis H37Rv P9WPP7
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.19.70 ammonium sulfate precipitation, phenyl Sepharose column chromatography, Q-Sepharose column chromatography, and hydroxyapatite column chromatography Mycobacterium tuberculosis

Subunits

EC Number Subunits Comment Organism
1.14.19.70 ? x * 43126, calculated from amino acid sequence Mycobacterium tuberculosis
1.14.19.70 ? x * 43128, electrospray ionization mass spectrometry Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
1.14.19.70 CYP121
-
 Mycobacterium tuberculosis
1.14.19.70 rv2276
-
 Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.70 heme
-
 Mycobacterium tuberculosis