EC Number | Cloned (Comment) | Organism |
---|---|---|
2.6.1.5 | expressed in Escherichia coli | Mus musculus |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.6.1.5 | through macromolecular crystallography the mTAT crystal structure is determined at 2.9 Å resolution. The crystal structure reveal the interaction between the pyridoxal-5'-phosphate cofactor and the enzyme, as well as the formation of a disulphide bond | Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.5 | 0.7 | - |
4-hydroxyphenylpyruvate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 0.9 | - |
phenylpyruvate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 1.8 | - |
2-oxoglutarate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 1.8 | - |
L-tyrosine | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 4.9 | - |
L-glutamate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 7.3 | - |
2-Oxohexanoate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 11.4 | - |
L-phenylalanine | pH 7.0, 38°C | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.5 | Mus musculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.6.1.5 | using affinity, Source-Q and gel-filtration chromatography | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.5 | L-glutamate + 4-hydroxyphenylpyruvate | - |
Mus musculus | L-tyrosine + 2-oxoglutarate | - |
? | |
2.6.1.5 | L-phenylalanine + 2-oxoglutarate | - |
Mus musculus | 2-oxo-3-phenylpropanoate + L-glutamate | - |
? | |
2.6.1.5 | L-tyrosine + 2-oxoglutarate | - |
Mus musculus | 3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate | - |
? | |
2.6.1.5 | L-tyrosine + 2-oxohexanoate | - |
Mus musculus | 3-(4-hydroxyphenyl)-2-oxopropanoate + (2S)-2-aminohexanoate | - |
? | |
2.6.1.5 | L-tyrosine + phenylpyruvate | - |
Mus musculus | 3-(4-hydroxyphenyl)-2-oxopropanoate + L-phenylalanine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.5 | mTAT | - |
Mus musculus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.6.1.5 | 38 | - |
assay at | Mus musculus |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.6.1.5 | 50 | 70 | highest activity | Mus musculus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.5 | 1.83 | - |
2-Oxohexanoate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 2.66 | - |
phenylpyruvate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 9.33 | - |
L-glutamate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 15.33 | - |
L-phenylalanine | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 15.83 | - |
4-hydroxyphenylpyruvate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 19.33 | - |
L-tyrosine | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 25.66 | - |
2-oxoglutarate | pH 7.0, 38°C | Mus musculus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.5 | 7 | - |
- |
Mus musculus |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.5 | 0.33 | - |
2-Oxohexanoate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 1.33 | - |
L-phenylalanine | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 2 | - |
L-glutamate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 3 | - |
phenylpyruvate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 10.66 | - |
L-tyrosine | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 14.16 | - |
2-oxoglutarate | pH 7.0, 38°C | Mus musculus | |
2.6.1.5 | 22.66 | - |
4-hydroxyphenylpyruvate | pH 7.0, 38°C | Mus musculus |