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Literature summary extracted from

  • Estarellas, C.; Frontera, A.; Quinonero, D.; Deya, P.
    Relevant anion-π interactions in biological systems: The case of urate oxidase (2011), Angew. Chem. Int. Ed. Engl., 50, 415-418.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.3.3 8-Azaxanthine anion-pi interactions are present in the active site of the enzyme and are energetically favorable. Uric acid and 8-azaxanthine are able to interact favorably with cyanide and chloride ions, respectively and both uric acid and 8-azaxanthine react with water Aspergillus flavus
1.7.3.3 CN- the presence of residue Phe159 enhances the interaction energy of the anion with the urate pi system Aspergillus flavus

Organism

EC Number Organism UniProt Comment Textmining
1.7.3.3 Aspergillus flavus Q00511
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-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.3.3 additional information anion-pi interactions are present in the active site of the enzyme and are energetically favorable Aspergillus flavus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.7.3.3 Uaz
-
 Aspergillus flavus