Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Villafane, A.A.; Voskoboynik, Y.; Cuebas, M.; Ruhl, I.; Bini, E.
    Response to excess copper in the hyperthermophile Sulfolobus solfataricus strain 98/2 (2009), Biochem. Biophys. Res. Commun., 385, 67-71.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.8 Saccharolobus solfataricus B2CQV8
-
-
7.2.2.8 Saccharolobus solfataricus 98/2 B2CQV8
-
-

Synonyms

EC Number Synonyms Comment Organism
7.2.2.8 CopA
-
 Saccharolobus solfataricus

Expression

EC Number Organism Comment Expression
7.2.2.8 Saccharolobus solfataricus Sulfolobus responds to exposure to a sublethal copper excess by the transient active transcription of the copA gene. The copA transcript reaches a peak 1 h after treatment, corresponding to approximately 35fold the uninduced level. Thereafter, the transcript level decreases until a steady-state level of 2-3fold induction is reached in the following 16 h. In cells cultured for several generations in the presence of 0.75 mM copper, the amount of copA transcript is maintained at 2-3fold the uninduced level, indicating that its rate of expression is maintained constant during longterm exposures, provided the concentration of copper do not change up

General Information

EC Number General Information Comment Organism
7.2.2.8 physiological function the constitutive expression of copTA probably provides a constant and low level supply of the protein CopT and the Cu+-exporting ATPase CopA that maintain homeostasis, allowing the cell to adjust to small fluctuations in copper levels under normal condition Saccharolobus solfataricus