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Literature summary extracted from

  • Sarkar, M.; Hunt, C.; Guzelian, P.; Karnes, H.
    Characterization of human liver cytochromes P-450 involved in theophylline metabolism (1992), Drug Metab. Dispos., 20, 31-37.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.178 microsome
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.178 theophylline + O2 + NADPH + H+ Homo sapiens i.e. 1,3-dimethylxanthine 3-methylxanthine + NADP+ + H2O + formaldehyde
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.178 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.178 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.178 theophylline + O2 + NADPH + H+ i.e. 1,3-dimethylxanthine Homo sapiens 3-methylxanthine + NADP+ + H2O + formaldehyde
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.178 P450-d
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.178 NADPH required Homo sapiens