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Literature summary extracted from

  • Lou, H.; Duan, Z.; Huo, X.; Huang, L.
    Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins (2003), J. Biol. Chem., 279, 127-132.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.11.1 additional information 7-kDa DNA-binding proteins are capable of significantly inhibiting the excision and enhancing the extension of matched template primers by the polymerase. The proteins do not protect single-stranded DNA from cleavage by polB1. The 7-kDa proteins do not affect the proofreading ability of polB1 and are not inhibitory to the excision of mismatched primers by the polymerase. The dNTP concentrations required for the effective inhibition of the 3'-5' exonuclease activity of polB1 are lowered from 1 mM in the absence of the 7-kDa proteins to 50 M in the presence of the proteins at 65 °C Saccharolobus solfataricus

Organism

EC Number Organism UniProt Comment Textmining
3.1.11.1 Saccharolobus solfataricus P26811
-
-
3.1.11.1 Saccharolobus solfataricus P2 P26811
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.11.1 single-stranded DNA + H2O 3'-5' exonuclease activity, degrades both single-stranded DNA and double-stranded DNA at similar rates Saccharolobus solfataricus ?
-
 ?
3.1.11.1 single-stranded DNA + H2O 3'-5' exonuclease activity, degrades both single-stranded DNA and double-stranded DNA at similar rates Saccharolobus solfataricus P2 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.11.1 POlB1
-
 Saccharolobus solfataricus
3.1.11.1 SSO0552 locus name Saccharolobus solfataricus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.11.1 65
-
 assay at Saccharolobus solfataricus